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Doctor insights on: Hla Typing

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Dr. Michael Dugan
10 doctors shared insights

Hla Typing (Overview)

Describes the determination of proteins on the cell surface which the immune system utilizes to assign self and not self. There are multiple genes which encode these proteins on chromosome 6.


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What is hla-typing or "tissue typing?" what is tissue crossmatch?

What is hla-typing or "tissue typing?" what is tissue crossmatch?

Donor-Recipient: These are all methods of determining compatibility between donor and recipient with organ and tissue transplants. Everyone has certain protein and carbohydrate markers on the outside of every cell. These make us unique, but also are potential allergens between people. To help prevent rejection (which can be life-threatening) we try to make sure the markers are alike as possible in both people. ...Read more

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Dr. Michael Dugan
10 doctors shared insights

Hla Typing (Overview)

Describes the determination of proteins on the cell surface which the immune system utilizes to assign self and not self. There are multiple genes which encode these proteins on chromosome 6.


2

2
What are indications of hla typing?

What are indications of hla typing?

Immunology: Usually hla typing is performed to look for immune compatibility (or lack thereof). Examples include transplant, platelet transfusion, and certain autoimmune diseases. ...Read more

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Lower abdominal discomfort, ultra/ct scans, bloodwork, esr, pst, colonoscopy, celiac hla typing, celiac panel all normal. Can it be ativan (lorazepam) withdrawal?

Lower abdominal discomfort, ultra/ct scans, bloodwork, esr, pst, colonoscopy, celiac hla typing, celiac panel all normal. Can it be ativan (lorazepam) withdrawal?

It is nonspecific sy: Your symptoms are not anything serious to justify anymore testing, as you already have done a lot. I would hold off any further interventions and eat and live normally. Begin to exercise daily would help to get your mind of this vague symptom of abdominal discomfort. ...Read more

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What are indications of hla typing?

Immunology: Usually hla typing is performed to look for immune compatibility (or lack thereof). Examples include transplant, platelet transfusion, and certain autoimmune diseases. ...Read more

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5
What is the definition or description of: hla typing?

What is the definition or description of: hla typing?

HLA typing: Describes the determination of proteins on the cell surface which the immune system utilizes to assign self and not self. There are multiple genes which encode these proteins on chromosome 6. ...Read more

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6
What is hla-typing or "tissue typing?" what is tissue crossmatch?

Donor-Recipient: These are all methods of determining compatibility between donor and recipient with organ and tissue transplants. Everyone has certain protein and carbohydrate markers on the outside of every cell. These make us unique, but also are potential allergens between people. To help prevent rejection (which can be life-threatening) we try to make sure the markers are alike as possible in both people. ...Read more

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With regards to hla typing, is mhc-1 matching or mhc-2 better to avoid a graft rejection?

With regards to hla typing, is mhc-1 matching or mhc-2 better to avoid a graft rejection?

In the arena of stem: Cell transplantation this is more defined than in the past. Class one match (hla a, b and c) and class two (hla dr and dq) are all performed at high resolution (gene level tryping). The best match with all loci evaluated will produce the lowest chance of graft rejection. Mis-match can be assessed in the gvhd and host vs graft (rejection) direction. ...Read more

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Lower abdominal discomfort, ultra/ct scans, bloodwork, esr, pst, colonoscopy, celiac hla typing, celiac panel all normal. Can it be ativan (lorazepam) withdrawal?

It is nonspecific sy: Your symptoms are not anything serious to justify anymore testing, as you already have done a lot. I would hold off any further interventions and eat and live normally. Begin to exercise daily would help to get your mind of this vague symptom of abdominal discomfort. ...Read more