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Doctor insights on: Glucosamine

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Dr. Abdolmohammad Rostami
242 Doctors shared insights

Glucosamine (Overview)

Glucosamine is one of several nutritional supplements that may aid in cartilage healing. There is not conclusive proof of its benefit.


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What can glucosamine do for you?

What can glucosamine do for you?

Agree with Wikipedia: The possible effects of glucosamine sulfate in patients with osteoarthritis may be the result of its anti-inflammatory activity, [50][51] the stimulation of the synthesis of proteoglycans, [52] and the decrease in catabolic activity of chondrocytes inhibiting the synthesis of proteolytic enzymes and other substances that contribute to damage cartilage matrix and cause death of articular chondrocytes.

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Dr. Abdolmohammad Rostami
242 Doctors shared insights

Glucosamine (Overview)

Glucosamine is one of several nutritional supplements that may aid in cartilage healing. There is not conclusive proof of its benefit.


Emily Lu Dr. Lu
7 doctors agreed:
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What exactly is glucosamine chondroitin?

Emily Lu Dr. Lu
7 doctors agreed:
What exactly is glucosamine chondroitin?

Cartilage Components: Glucosamine is a modified sugar that can be crosslinked to form shellfish shells and glycosaminoglyans, a major component of connective tissue. Chondroitin sulfate is a particular kind of glycosaminoglycan that is especially prevalent in cartilage and is often depleted during osteoarthritis..

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How do you take glucosamine?

How do you take glucosamine?

Orally: This is usually available otc in pill/tablet form and is taken orally. (glucosamine/chondroitin). For dosing, follow the lable or manufacturers recommendaitons.

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Please tell me can glucosamine be used as a preventative measure?

Yes: Yes, glucoasmine can help prevent the progression of arthritis which is what it has been approved to treat. It must be used for as least 4 months to see benefit. I would recommend pairing it with chodroitin, the pill may come with both. This is the best to help maintain cartilage.

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Is glucosamine effective against arthritis?

Is glucosamine effective against arthritis?

Modest benefits.: Some people in medicine believe not, and I am among those. Others believe some benefit occurs. Notice that the fda has not allowed any such products to be labeled as effective. I point to the cochrane analysis, which suggests no benefit. 3 billion dollars are spent on these supplements!

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Can glucosamine work on osteoarthritis in both knees?

Sometimes: There is no harm in trying. Take at least 1, 500 mg daily and give it a 3 month trial before deciding how much it does or does not help.

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I am currently taking cod liver oil glucosamine chondroitina and 10pg of vit d. .. I wish to take calcium magnesium too but has 5.0 vit d isit ok?

Calcium not needed: Recent studies have shown that large doses of vitamin d are not advisable. Also, studies suggest that supplemental calcium also has little or no benefit.

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Are there any side effects of glucosamine for arthritis?

Are there any side effects of glucosamine for arthritis?

Elevated blood sugar: Aside from that, which pre-diabetics and diabetics need be aware. Virtually none. A cochrane analysis (medical think tank) found no conclusive benefits from this or chondroitin sulfate. I am the side that does not think it works. Last year $3.8 billios dollars were spent on this product alone. Check the label: fda does not endorse this product for treatment of any disease!

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What are the risks of glucosamine causing diabetes, especially with the long term use?

Unknown, unlikely: In the short term, glucosamine has not been shown to have any affect on sugar or developing diabetes. Long-term affects are unknown, but no evidence exists to suspect that long-term use of glucosamine will lead to a higher risk of developing diabetes. Further studies are needed to prove this though.

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Is it okay to take a combination of glucosamine and chondroitin?

Is it okay to take a combination of glucosamine and chondroitin?

Yes: Most products are sold together. Unless pt. Has allergy to it or has uncontrolled diabetes or hypertension majority of pts. Have no problems.

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How much glucosamine supplement do I take?

How much glucosamine supplement do I take?

It is not known yet: The best dose of glucosamine is not known. Most research studies have used doses of 1, 200 to 1, 500 mg per day, usually in two or three separate doses. Because supplement manufacture is more loosely regulated than drug manufacture and producers voluntarily follow good manufacturing practices, purchase glucosamine from a reputable supplier.

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There are many pills with glucosamine and chondroitin. Are these the best for joints?

There are many pills with glucosamine and chondroitin. Are these the best for joints?

Yes: The combination of glucosamine and chondroitin has been shown in studies to (1) provide a degree of pain relief in the short term, and (2) trigger growth of new cartilage when taken for at least two years straight. So it can help you pain and reverse some of the chronic damage. You can find this in the health food store. MSM is not necessary and adds to the cost of the product.

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How do you take glucosamine?

Orally: This is usually available otc in pill/tablet form and is taken orally. (glucosamine/chondroitin). For dosing, follow the lable or manufacturers recommendaitons.

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What can glucosamine do for you?

Agree with Wikipedia: The possible effects of glucosamine sulfate in patients with osteoarthritis may be the result of its anti-inflammatory activity, [50][51] the stimulation of the synthesis of proteoglycans, [52] and the decrease in catabolic activity of chondrocytes inhibiting the synthesis of proteolytic enzymes and other substances that contribute to damage cartilage matrix and cause death of articular chondrocytes.

See 2 more doctor answers