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Doctor insights on: Does Hepatitis Vaccine Cause Liver Enzyme Abnormalities

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Can hepatitis b vaccine given in 1986 cause elevated liver enzymes?

Can hepatitis b vaccine given in 1986 cause elevated liver enzymes?

Should not be...: A hepatitis b vaccination given 27 years ago should not be the cause of elevated liver enzymes currently. ...Read more

Dr. Michael Gabor
2 Doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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Can the INFANRIX HEXA vaccine (which includes Hepatitis B) cause elevated liver enzymes AST and ALT? If yes, is this dangerous for an infant?

Can the INFANRIX HEXA vaccine (which includes Hepatitis B) cause elevated liver enzymes AST and ALT? If yes, is this dangerous for an infant?

2 answers:: 1. Hexa contains only a single protein component of Hep B and cannot cause Hepatitis by itself;

2. AST/ALT elevation can be a sign of a significant problem in an infant, and needs a thorough workup. With problems such as biliary atresia or galactosemia, this needs to be done sooner rather than later. ...Read more

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Can acute hepatitis be a sign of permanent liver disease even if liver enzyme levels go back to almost normal?

Can acute hepatitis be a sign of permanent liver disease even if liver enzyme levels go back to almost normal?

Acute hepatitis: Is a form of liver disease. Most people recover from acute viral hepatitis. Unfortunately some cases progress to chronic aggressive form of disease, which can lead to cirrhosis. So have your doctor keep an eye on you. ...Read more

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Liver enzyme level ALT 54 (slightly elevated). What levels do they reach if a person has hepatitis a, b and c?

Really Variable: In general, with chronic hepatitis c the levels can fluctuate between normal and usually not >300-400. Acute HAV and hbv can have levels in the 1, 000s. Chronic hbv can settle with levels similar to that in hcv. Hav does not cause chronic disease. ...Read more

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Can I have a normal liver enzyme (e.G., alt) level and still have chronic hepatitis c?

Can I have a normal liver enzyme (e.G., alt) level and still have chronic hepatitis c?

Oh yes: Some patients with chronic hep c may have normal liver enzymes, or normal enzymes intermittently. Liver function tests (lfts) are not the marker of the disease, or success of treatment; viral load is. Inflammation, scarring is more closely related to viral load and immune response to it. ...Read more

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Elevated liver enzyme with normal other liver function and normal ultrasound and negative hepatitis b and c virus??

Elevated liver enzyme with normal other liver function and normal ultrasound and negative hepatitis b and c virus??

2 thoughts:: A common cause of asymptomatic elevations in liver enzymes is fatty liver (Non alcoholic fatty liver disease: NAFLD). This is very common in obesity and is considered
to be part of the metabolic syndrome. Ultrasound will be "normal" (i.e. falsely negative) in 17% of patients with NAFLD.

A less common cause=choledocholithiasis (stones in common bile duct). Often missed on ultrasound. Can be
asymptom ...Read more

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Can acute hepititis be a sign of liver disease even if liver enzyme levels go back to near-normal?

Can acute hepititis be a sign of liver disease even if liver enzyme levels go back to near-normal?

Depends on cause: Almost all people recover completely from hep a, about 80% recover fully from hep b, only about 20% recover fully from hep c. Other causes of hepatitis, such as cmv, mono are usually transient. Alcoholic hepatitis and non-alocholic steatohepatitis can lead to permanent damage, . ...Read more

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Elevated liver enzymes. ALT- 72 AST- 59. ALL other labs are normal. Liver/gallbladder ultrasound is normal. Negative for hepatitis. What can cause it?

Elevated liver enzymes. ALT- 72 AST- 59. ALL other labs are normal. Liver/gallbladder ultrasound is normal. Negative for hepatitis. What can cause it?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it may be due to alcohol intake, medications you may be taking and/or from being overweight. If you drink, stop entirely and discuss any medications you take with your doctor. ...Read more

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I was told hepatitis liver enzymes would be in the 1000's and most other serious liver disorders are in the 100's. What are normal levels?

I was told hepatitis liver enzymes would be in the 1000's and most other serious liver disorders are in the 100's. What are normal levels?

Why do you ask?: Transaminases (sgot/ast, sgpt/alt) are usually below 40. In acute alcoholic or viral hepatitis, levels may be as low as the 400's with the person obviously sick. However, we draw them to look for smoldering, subtle disease (wilson's, chronic hepatitis, hemochromatosis, drug sensitivity, autoimmunity, nafl) and if your physician wants to work you up, it's your choice -- if missed, they can kill you. ...Read more

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My liver enzymes are elevated, but I tested negative for hepatitis, could I have liver disease or cancer?

My liver enzymes are elevated, but I tested negative for hepatitis, could I have liver disease or cancer?

Possibly, not likely: Meds, supplements and alcohol can elevate your liver enzymes. Chronic hepatitis c is common, so make sure they tested for it. The first step is to make sure whatever you put in your mouth isn't hurting your liver, and follow your test results over time. About 9% of adults have abnormal lfts. Obesity causing fatty liver is another common cause. I'm not sayin' you're fat, but had to mention it! ...Read more

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Husband had non-speciific hepatits 10 yrs ago. OK now. My liver enzymes were elevated - ok now. What do I tell my doctor re hepatitis?

Impossible: It is not ten years ago now. If you had infectious hepatitis you doctor should know and be able to test you to determine if you are infected, have been infected and cleared the infection or if you are still actively infected. Having normal liver functions does not in any way answer these questions. ...Read more

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Anyone know what is a reason other than hepatitis for liver enzymes to be elevated in the blood?

Yes: Numerous issues can increase enzymes such as numerous meds and many other diseases. Also the ast and alt can also be elevated by certain muscle diseases. ...Read more

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High liver enzymes and hepatitis! What are effects?

High liver enzymes and hepatitis! What are effects?

Depends. Check w/MD: Hepatitis means liver inflammation-lots of causes, including several viruses, parasites, drugs, toxins, alcohol, immunologic, pregnancy associated changes, etc. May have symptoms, e.g. Nausea, poor appetite, weight loss, abnormal physical, e.g. Jaundice, abdominal fluid, altered mental status, etc. Some are self limited; others can lead to chronic disease, cirrhosis, liver failure. Check with md. ...Read more

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I am working in cambodia. I have elevated liver enzymes (alt 149) & GGT is 280. Is it safe to get hep a & b vaccines? Liver sonogram normal -

Get serology first,,: Before you even think of getting vaccinated it'd be good to get a serologic result to see if you've already been exposed and made antibodies to hep a, b or the other hepatitis viruses. You might have contracted one of them without knowing it. Next, more liver tests/other tests would be needed to find out why your enzymes are elevated. You might have gone to an area endemic for malaria, etc.. ...Read more

Dr. Mark Diamond
1,098 Doctors shared insights

Vaccinations (Definition)

Latin word for cow, vacca, because of the smallpox/cowpox work of edward jenner, vaccination is the administration of a substance, live organism or otherwise, that stimulates the immune response to prevent a specific disease. Primarily a preventative procedure, some vaccines can ...Read more


Dr. Mark Diamond
1,091 Doctors shared insights

Immunization (Definition)

The body is artificially exposed to a dead or weakened organism of a type able to cause disease. The body fights the organism and learns to protect itself, so disease will not develop if exposed to ...Read more