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Doctor insights on: Does Deep Brain Stimulation Become Less Effective Over Time

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Does deep brain stimulation become less effective over time?

Does deep brain stimulation become less effective over time?

Yes: Over time, the generator can become depleted and require replacement. Also, the disease which is being treated can progress and become less responsive to dbs. ...Read more

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Dr. Robert Hutchman
91 doctors shared insights

Deep Brain Stimulation (Definition)

Deep brain stimulators are used in the treatment of parkinson's and tremors. A person is scanned with a MRI or ct frame on their head. A burrhole is then made and a stimulator wire is passed into a precise deep brain target. This is connected to a stimulator which placed under the skin. They are very expensive but ...Read more


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If ADHD meds desensitize brain receptors over long periods of time, then how come having an orgasm or two every day doesn't do so substantially more?

If ADHD meds desensitize brain receptors over long periods of time, then how come having an orgasm or two every day doesn't do so substantially more?

Interesting question: ADHD meds work differently in the same person at different points in time. Desensitization does not necessarily occur in all people. The latter situation, unfortunately, will likely abate over time. Someday you will look back upon what things were like back when you were 26 with mixed feelings. Those with significant cognitive dysfunction would not be able to generate a question like this. ...Read more

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Does the improvement in conc. That nicotine causes disappear over time as the receptors become desensitized and smoker increases dependency?

Does the improvement in conc. That nicotine causes disappear over time as the receptors become desensitized and smoker increases dependency?

No: Tolerance does not develop to all effects of dependency-producing substances at the same rate, and nicotine seems to be able, even in relatively small doses, improve concentration and focus; withdrawal from nicotine however produces a marked disruption of concentration and focus that can be disabling, particularly to people with jobs that require it. ...Read more

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Concentration just degraded over time as my depression became more intense. Does depression cause this?

Concentration just degraded over time as my depression became more intense. Does depression cause this?

Yes: Oh my yes. Increased depression can cause marked drops in concentration. If not already doing so, please accept professional help. Take care. ...Read more

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If taking melatonin every night does the brain produce less and less melatonin?

If taking melatonin every night does the brain produce less and less melatonin?

No there is no evide: No there is no evidence that it makes brain produce less and less or it suppresses the production of malitonin. ...Read more

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Can a seizure lasting longer than 5 minutes but less than 15 minutes damage a three year olds brain or even worse be fatal?

Can a seizure lasting longer than 5 minutes but less than 15 minutes damage a three year olds brain or even worse be fatal?

Not Likely: Seizures lasting less than 20-30 minutes almost never cause any injury in an otherwise healthy child. A fatality from a seizure this length would be almost unheard of as usually, it isn't the seizure that injurs the child, but what they were doing when the seizure occurred that caused the problem (climbing a tree, in the bathtub, etc). ...Read more

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2nd time around on olanzapine. Become more sensitive to the sedative effects at same dose. Guessing it's an inevitable feature of the drug, but does sedation diminish with time? If so, how long?

2nd time around on olanzapine. Become more sensitive to the sedative effects at same dose. Guessing it's an inevitable feature of the drug, but does sedation diminish with time? If so, how long?

Lower the dose.: If you have not taken Olanzapine for a while, you may feel like you are taking it for the first time. Some people take at least 2-3 weeks to get used to it. Let your doctor know and you may have to start at a lower dose . You may even respond at a that lower dose. Good luck. ...Read more

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How effective is red light to heal lesions at 650 nm, will it promote healing or is light therapy a waste of time?

How effective is red light to heal lesions at 650 nm, will it promote healing or is light therapy a waste of time?

Cold laser: Cold laser is well known to promote healing. It is used in europe quite a lot (unfortunately not in the usa-due to fda). I would think that its not a waste of time and to certainly try it. Make sure its a medical grade laser and max treatments are 12 but you should see a difference by 6-7 treatments if done right. ...Read more

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Are Ssris bad for the Brain and the body when used in long term ? I'm on Zoloft (sertraline) for anxiety but I'm very nervous that it might damage or change me when used for a few years or longer ?!

Are Ssris bad for the Brain and the body when used in long term ? I'm on Zoloft (sertraline) for anxiety but I'm very nervous that it might damage or change me when used for a few years or longer ?!

Usually a great med: 100,000s if not millions of people have used this type of medication for such a time period. There are many studies which show it is safe. Of course there are possible side effects and occasional drug interactions that your doctor would recognize if you discussed any concerns with him or her. Sometimes psychotherapy is needed in addition or instead of meds Discuss your concerns with your doctor. ...Read more

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Can a fixed drug eruption on penis head stay more than 7 months? Mine is gradually becoming better. All meds stopped.Does sexual activity prolong it?

Can a fixed drug eruption on penis head stay more than 7 months? Mine is gradually becoming better. All meds stopped.Does sexual activity prolong it?

See below : Diagnosis of fixed drug reaction is based on history, physical exam, and exclusion of other causes of penile lesions. Most common drug classes implicated: analgesics, muscle relaxants, sedatives, anticonvulsants, and antibiotics (sulfa, PCN, tetracycline). Acute Rx: stop drug, topical or oral steroids, antihistamine. Not uncommon to have residual hyper pigmentation after acute lesion resolves. ...Read more

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Does a brain revert back to a less intelligent state if psychiatric meds are discontinued? Can one create new neural pathways by hard work and trying

Does a brain revert back to a less intelligent state if psychiatric meds are discontinued? Can one create new neural pathways by hard work and trying

No and absolutely!: Many psychiatric disorders impair thinking, concentration, memory, and problem solving. Medications may allow your brain to achieve more of its potential by helping to relieve symptoms. Some medications may slightly temporarily improve cognition (modafinil, caffeine). But the great thing is that your brain will respond to demand; its called "neuroplasticity". Use it and grow it! ...Read more

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Does artery inflammation change - worse at times, less inflammation at others (i do not mean in response to medication / treatment)? Pos. Factors?

Does artery inflammation change - worse at times, less inflammation at others (i do not mean in response to medication / treatment)? Pos. Factors?

See below: In reference to the other questions that you have posted, when one is on Prednisone we follow patients symptoms and inflammatory markers such a sed rate and crp. ...Read more

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Mastrube with moving hand slowly takes large time may 15 mintes but when moves quikly take very small time 2 min ..iam premature ejacualtion or not ?

Mastrube with moving hand slowly takes large time may 15 mintes but when moves quikly take very small time 2 min ..iam premature ejacualtion or not ?

Enjoy yourself: young man, what does this matter? When you start sharing yourself with a partner, be yourself......and if any ejaculation issues trouble the relationship, then ask if it's a problem. Go share it.....but protect everyone involved by making safe decisions, and use a condom for unwanted pregnancy or disease. Zmd ...Read more

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If i breath from one nostril alternative does it cause less oxygen supply to my body or brain ?

If i breath from one nostril alternative does it cause less oxygen supply to my body or brain ?

No: No, because one would automatically breathe all the necessary air through the other nostril. If that doesn't work out, he can just open his mouth. ...Read more

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Can deep brain stimulation treatment help Parkinson's patients with more than the shaking?

Can deep brain stimulation treatment help Parkinson's patients with more than the shaking?

Yes: Deep brain stimulation can help patients with all three cardinal motor symptoms of parkinson's disease, including tremor, rigidity (or stiffness), and slowness (bradykinesia). It does not help with non-motor symptoms, balance problems, or freezing. ...Read more

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