Doctor insights on:
Can Men With Sickle Cell Disease Have Children
An inherited blood disease causing red blood cells to be sickle (curved) shaped instead of round. It shortens life expectancy, and can result in bacterial infections, painful swelling of the hands and feet, fever, arthritis, leg ulcers, fatigue, anemia, eye damage, and ...Read more
Yes.: Sickle cell disease must be inherited from both parents. So it depends on the mother of the child. If she has sickle cell - all of your children will have sickle cell. If she has sickle cell trait - there is a 50% chance your children will have sickle cell disease, and a 50% chance of your children having sickle cell trait. If she has no sickle cell - your children will have sickle cell trait. ...Read moreSee 1 more doctor answer
YES: Be sure to let your obstetrician know you have sickle cell so you can be managed correctly. ...Read more
Proper care needed: As long as they are under proper medical attention there should be no problem. ...Read more
Yes: Hydre increases a type of hemoglobin called fetal hemoglobin in sicle cell patients and this prevents the sickle cells from breaking up easily. Hydrea (hydroxyurea) can reduce need for transfusions and patients may have less pain crises, chest sydrome and other complications. ...Read moreSee 1 more doctor answer
No: People with Alpha thalassemia trait are similar to regular people. Some Alpha thal. Trait persons are mildly anemic, but the anemia is not enough to cause symptoms. A few people may be anemic enough to feel tired or have pallor (pale appearance). Intestinal problems, and other medical problems, can occur just as they occur in non-thalassemic persons. ...Read moreSee 1 more doctor answer
99+% yes: The answer is yes, but there is always a chance of a new mutation (rare). In which case one of the parents might not have trait. There is also hemoglobin c which can combine with hemoglobin s to give a very similar clinical disease (hemoglobin sc disease). You can also have sickle beta thalassemia which is very similar to sickle cell disease. But only one parent has to have sickle trait. ...Read more
Yes: In the treatment of sickle-cell disease, hydroxycarbamide increases the concentration of fetal hemoglobin. The precise mechanism of action is not yet clearbut it seems to activate of gammaglobin synthesis necessary for fetal hemoglobin. This stops the rapidly growing cells that turn into sickle cells. ...Read moreSee 2 more doctor answers
Yes!: Different diseases!Get a more detailed answer ›
Genetics: Sickle cell disease must be inherited from both parents. Sickle cell trait (1 sickle gene, 1 normal gene) is usually asymptomatic. 2 persons with sickle cell trait have a 1/4 chance of having a child with sickle cell disease, but the parents are often unaware that they have anything. ...Read moreSee 2 more doctor answers
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