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Doctor insights on: Can I Take Benadryl With Flexeril

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What is flexeril? Why take it with benadryl (diphenhydramine)?

What is flexeril? Why take it with benadryl (diphenhydramine)?

[email protected]: Flexeril is a muscle relaxant, its generic name is cyclobenzaprine, it does not have to be taken with Benadryl (diphenhydramine) to be effective. But it can be taken with benadryl, (diphenhydramine) but be careful, it will cause sedation. ...Read more

Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Is it okay to take Benadryl (diphenhydramine) with a flexeril?

Is it okay to take Benadryl (diphenhydramine) with a flexeril?

Should be ok: Benadry is an anti-allergy (anti-histamine) and Flexeril (cyclobenzaprine hcl) is essentially a serotonin anti-depressant med. But you might feel a little extra sleepy, so be careful about machinery/driving etc and try it out with some supervision the first time b/c everyone has individual reactions. ...Read more

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I was told by a doctor to take benydryl but I'm precribed flexeril (cyclobenzaprine hcl) is that safe to take together at 35wks pregnant?

I was told by a doctor to take benydryl but I'm precribed flexeril (cyclobenzaprine hcl) is that safe to take together at 35wks pregnant?

Yes: Both are considered pregnancy category B and thus should be safe although you may get additive drowsiness effect by taking both. As always, try to minimize your medication intake pregnant or otherwise. ...Read more

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I am suffering with sinusg congestion, and I am taking elavil, flexaril, and Neurontin at night. What can I take to help. I have alahist, benadryl (diphenhydramine)?

I am suffering with sinusg congestion, and I am taking elavil, flexaril, and Neurontin at night. What can I take to help. I have alahist, benadryl (diphenhydramine)?

Depends: If the problem is from an allergy, then steroid nasal spray would likely be helpful. I would advise against using any oral nasal decongestant. See allergist if problem fails to improve with nasal steroid. ...Read more

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Is it Ok to take zzzquil now if I took a flexeril at 2pm?

Is it Ok to take zzzquil now if I took a flexeril at 2pm?

Seek advice: The 2 can interact with each other to cause a variety of side effects see below:
https://www. Drugs. Com/interactions-check. Php? Drug_list=758-386, 896-16076

It depends what you were doing (might be risky if driving or operating heavy machinery for instance). Safest approach here is to seek advice from a doctor or pharmacist licensed in your area. ...Read more

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What happens if you take too much benadryl (diphenhydramine)?

Benadryl (diphenhydramine): It ususally makes you have a dry mouth and get very sleepy. ...Read more

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Is it okay if to take 2 benadryls (diphenhydramine) and I melatonin?

Is it okay if to take 2 benadryls (diphenhydramine) and I melatonin?

Doses?: Depends on the dose of Benadryl (diphenhydramine). If you have insomnia, sleep hygiene is an often overlooked, yet more effective treatment, than medications. In addition, the combination of medications could impair decision making, cause undesired drowsiness, and other side effects. Speak with your doctor, before taking any combination of medications. Do not drive/operate heavy machinery under their influence. ...Read more

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Would it be ok to take Benadryl (diphenhydramine) that expired in 11/09?

Would it be ok to take Benadryl (diphenhydramine) that expired in 11/09?

Benadryl (diphenhydramine): Taking medication that expired almost 5 years ago is probably not a good idea. It may be safe, but I don't know for sure. If we were in the Zombie apocalypse and you had no other choice I would say go for it. But since generic diphenhydramine is cheap, why don't you make a trip to your local store and buy some new. ...Read more

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What would happen if someone takes a Benadryl (diphenhydramine) & 5mg vicdion together?

More sleepy: Nothing serious at these low doses although you may feel more sleepy since the sedation effects of ech medicine add up. But it should be fine after 12-18 hours. ...Read more

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Can you take meloxicam and Benadryl together?

Can you take meloxicam and Benadryl together?

Should be ok if...: If a person had no problems taking meloxicam (Mobic) in the past for some medical condition, and separately had no problem taking diphenhydramine (Benadryl) in the past, then she should be ok taking the medications at the same time. If worried, she can ask her doctor who prescribed the meloxicam. Benadryl does cause drowsiness, so can be unsafe for certain activities such as driving or piloting. ...Read more

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Can I take Benadryl (diphenhydramine) for hives?

Can I take Benadryl (diphenhydramine) for hives?

Yes: Benadryl (diphenhydramine) can make you drowsy so be cautious if you drive or do other activity. You need to see your physician to clarify why you have the hives. ...Read more

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Is it okay to take Benadryl on top of trazadone?

Increased sleepiness: Trazodone and benadryl are both medications that can be sedating. In general it would be safe to use them together with the caution that the sedating effects would be greater. It may be best to check with your physician to see if this is the right choice for you. ...Read more

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Can you take seroquel (quetiapine) with flexeril?

Can you take seroquel (quetiapine) with flexeril?

Ask your doctor: Many drugs have interactions with each other and that includes this combination. Both of these meds. Have a "sedative" like effect and the combination is at minimum additive. If you have been on one medication for some time than the second will likely be less prone to cause an issue than were you to start both at the same time. This is an issue that a professional should be actively managing. ...Read more

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Would it be fine to take adderall with a benadryl?

Would it be fine to take adderall with a benadryl?

Talk 2 dr/pharmacist: There are no particular drug-drug interactions, but we don't know what other medications you are on, or what your other health issues are. Benadryl is mildly sedating and may antagonize some of the effects of adderall. An occasional benadryl for an allergic problem or insomnia is likely to be fine, while regular use of it may be a problem for you. Talk to your prescriber and/or your pharmacist. ...Read more

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Can I take Benadryl (diphenhydramine) with allegra?

Can I take Benadryl (diphenhydramine) with allegra?

Yes: You can take them together. If you are sensitive to the sedating effects of antihistamines, you should not take them at the same time. It would be better to take Allegra in the morning or afternoon and then Benadryl (diphenhydramine) in the evening before bed. However, if you don't feel sleepy after taking antihistamines, it would not be harmful to take them together. ...Read more

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Can I take Claritin with benadryl (diphenhydramine)?

Can I take Claritin with benadryl (diphenhydramine)?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Can I take Benadryl (diphenhydramine) after claritin?

Can I take Benadryl (diphenhydramine) after claritin?

2 antihistamines: Even though both Benadryl (diphenhydramine) and Claritin are both antihistamines, there should not be significant interaction or side effects if taken at the usual doses. ...Read more

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Cani take Benadryl (diphenhydramine) with loratadine?

Probably yes.: Many people report their 'daily' non-sedating antihistamine in the am does not provide relief until next am. So, if no concerns for gu/heart/bp/med-conflict issues, then they often take a 'sedating' antihistamine at night for continued symptom relief and 'bonus' of sleep aid effect. ...Read more

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Can u take Valium with flexeril (cyclobenzaprine hcl)?

Can u take Valium with flexeril (cyclobenzaprine hcl)?

Not good: Valium is a great muscle relaxant, but also a sedative. Same with flexeril (cyclobenzaprine hcl). 1 or the other but not together. ...Read more

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Can you take Benadryl (diphenhydramine) with claritin?

Yes: There is no interaction. Since Claritin (loratadine) does not cause drowsiness side effects should not be a problem. However, if Claritin (loratadine) is not solving the problem, alternatives such as Allegra or zyrtec should be considered. ...Read more

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Can expectant mothers take benadryl (diphenhydramine)?

Probably: It is a category B drug that is usually safe during pregnancy. I would ask your OB to be complete and let him know any OTC medications you are taking ...Read more

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Can you take amox with flexeril (cyclobenzaprine hcl)?

Yes: If you are referring to amoxicillin, then yes you can take them together. ...Read more

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Can I take hydrocodone with benadryl (diphenhydramine)?

Yes: But both are sedating, so start with a low dose. Discuss it with your doctor. ...Read more

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I took reactine six hours ago can I now take benadryl?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Is it safe to take Vyvanse and benadryl (diphenhydramine)?

Safe but not advised: Benadryl (diphenhydramine) is too sedating, resulting often in some cognitive suppression. The reason for taking the Vyvanse in the 1st place is to enhance cognition. There are better antihistamines. And, if the purpose of the Benadryl (diphenhydramine) is to help sleep at night, there are better choices. ...Read more

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Could I take Benadryl while taking toprol (metoprolol) xl?

Yes you can: There are no interactions between two medications. However, Benadryl (diphenhydramine) can cause drowsiness so don't drive while taking it. ...Read more

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Is it okay to take zyrtec with benadryl (diphenhydramine)?

Not really: These are both antihistamines. If both are needed then physician guidance should be sought. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Syed H. Sajid
313 Doctors shared insights

Cyclobenzaprine Hcl (Definition)

Cyclobenzaprine HCl is a muscle relaxant which is a ...Read more