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Doctor insights on: Bupropion Fluoxetine Conbination

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Which is more effective: bupropion and fluoxetine?

Which is more effective: bupropion and fluoxetine?

That depends: Fluoxetine is very helpful in treatment of typical depressive disorders & anxiety. Bupropion is effective in treatment of atypical depressive disorders & smoking cessation. They can be used together for a mixed picture. ...Read more

Dr. Heidi Fowler
1,053 Doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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Will I gain weight taking 150 mg a day of bupropion xl and 30 mg of fluoxetine?

Will I gain weight taking 150 mg a day of bupropion xl and 30 mg of fluoxetine?

Probably not: The two medications you mention rarely induce weight gain. In fact, bupropion is one of the ingredients in a new FDA approved medication for weight loss. I have never had a single patient in my practice gain weight taking fluoxetine. ...Read more

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Can any one or combination of these cause slight visual and tactile hallucinations? Wellbutrin (bupropion) XL, Lamotrigine, Fluoxetine.

Can any one or combination of these cause slight visual and tactile hallucinations? Wellbutrin (bupropion) XL, Lamotrigine, Fluoxetine.

Maybe: "Slight" hallucinations? None of the three medications typically causes hallucinations. However bupropion (Wellbutrin) increases the risk of seizures and this is a possibility here. Tactile hallucinations are rare and usually seen in drug/alcohol intoxication/withdrawal. Please see your MD right away, these symptoms are unusual and potentially serious and require a medical explanation. ...Read more

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Currently on bupropion 200mg twice a day and I am on 10mg of prozac (fluoxetine). I want 2 start garcinia cambogia and wanted 2 know if it's safe taken separately?

Poor reviews: There are many negative reviews of this product with respect to its effectiveness. It may not have dangerous side effects or interactions w/ your other drugs - but it might not be worth the risk - never mind to cost. It must be troubling that weight gain is a side effect of your meds, but more meds don't seem like the best solution. Consider a combo of diet/exercise and planned reduction of meds. ...Read more

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What could cause frequent pvcs (benign) daily? Bupropion XL 150mg 3x daily, Prozac (fluoxetine) 20mg, or the combo? Also take 200mg modafinil, levothroid 88mcg.

What could cause frequent pvcs (benign) daily? Bupropion XL 150mg 3x daily, Prozac (fluoxetine) 20mg, or the combo? Also take 200mg modafinil, levothroid 88mcg.

Your medications: The Modafinil is a stimulant which can cause abnormal hearth rhythms. Your levothroid, if not properly dosed could do it as well, ask your doctor for a blood test to make sure that dose is not too high for you. Being 58 years old, you could have heart problems unrelated to the medications. You should see a doctor to get this evaluated. ...Read more

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Is Wellbutrin (100mg 2x/day), Fluoxetine (30mg) and Abilify (aripiprazole) (1mg, 2mg after a week) a safe combination for anxiety and depression?

Is Wellbutrin (100mg 2x/day), Fluoxetine (30mg) and Abilify (aripiprazole) (1mg, 2mg after a week) a safe combination for anxiety and depression?

Probably: Depending on yourneeds the combination seems reasonable. If the fluoxetine alone or in combination with wellbutrin doesn't remove/reduce depression, the addition of Abilify (aripiprazole) often helps. If, after a time this is not helpful... you didn't say you were in psychotherapy, but I would recommend it also. ...Read more

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Switched from Prozac (fluoxetine) 2 brupropion 75mg 2xpd having dull headache and sore calfs an thighs. Is this normal and how long should I try 4?

Switched from Prozac (fluoxetine) 2 brupropion 75mg 2xpd having dull headache and sore calfs an thighs. Is this normal and how long should I try 4?

Change: Talk to your doctor when ever switching medications there are some side effects which gradually go away headache and tachycardia is one of side effects best is to start low and go slow. ...Read more

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Is Yohimbine safe to use while on Fluoxetine, Abilify, (aripiprazole) Buproprion and a very low dose of Propranolol? Meds for anxiety. Klonopin as needed.

Is Yohimbine safe to use while on Fluoxetine, Abilify, (aripiprazole) Buproprion and a very low dose of Propranolol? Meds for anxiety. Klonopin as needed.

The risk here is: Between All the others you list! Some are very risky! Be sure your provider is watching you closely and try to stop some. ED is not your biggest worry and Yohimbine has side effects. Be careful - if your provider is not a psych specialist - you might want a consult when multi-pharma issues arise. Add CBT Tx for best outcome and less risks. You're too young for so many meds. Best! ...Read more

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Could I be on wellbutrin (bupropion) if my already taking Prozac and lithium?

Wellbutrin/Prozac: Wellbutrin (bupropion) is often used in addition to an antidepressant like Prozac to help control the sexual side effects of prozac, which can include the inability to have an orgasm. ...Read more

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Due to my Dr. He want 2 modify my combo as :reduce Prozac from 40 to 20 mg and increase Wellbutrin (bupropion) Xl from 150 to 300 mg, how can I apply that by safe?

Should be okay: That change should be safe to implement simultaneously, you may want to talk to your doctor about taking the lower dose of fluoxetine for a week and then taking the higher dose of the bupropion extended release although that is a just a precautionary move and largely unnecessary for many patients. Stay in close touch with the office of the prescribing physician during the transition! Stay safe! ...Read more

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My wife had an affair with my best friend. I am devastated. On Prozac and wellbutrin (bupropion) xl. It's been 7 mos. Why can't I stop obsessing about the details?

Double betrayal: With this one event, you have had two overwhelming losses. Your relationship with both your wife and your best friend are forever changed. Your medication won't change that. I hope the meds might help blunt the pain sufficient for you to function at your job. I strongly recommend psychotherapy for you and couples' therapy with you and your wife, if the two of you are trying to stay together. ...Read more

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My husband is on prozac/wellbutrin combo for a while. Will this affect male fertility?

My husband is on prozac/wellbutrin combo for a while. Will this affect male fertility?

Maybe: Some ssris (prozac) have been associated with increased levels of sperm dna fragmentation which could lead to infertility or miscarriages. However, it is only one study that needs confirmation. This information needs to be balanced by the increased quality of life associated with taking the medications. You can check for sperm dna fragmentation and know for sure. ...Read more

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I take both Prozac and wellbutrin (bupropion) daily - what will happen if I do cocaine while taking these medications?

I take both Prozac and wellbutrin (bupropion) daily - what will happen if I do cocaine while taking these medications?

Meds & street drugs: Use of any illicit drug its self damaging to brain system makes life long irreversible changes in the neuronal circuitry. Combining with meds is never a good idea and can cause opposing effects that can be making mood and anxiety symptoms worse and at times difficult to treat. If you still need to use a substance to covet for mood and anxiety meds your current meds are not well talk to psychiayrst. ...Read more

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My son, 18, is taking 80 mg of Prozac and 75 mg of Wellbutrin for OCD. He is relapsing. He has been on this for two years. What are some choices?

My son, 18, is taking 80 mg of Prozac and 75 mg of Wellbutrin for OCD. He is relapsing. He has been on this for two years. What are some choices?

Decisions: 18 is a challenging age. Your son can consent for treatment as he is of age. Important to clarify whether or not he is still taking his meds as many teens stop when they are of consenting age. Cognitive behavioral therapy is also an effective form of treatment for OCD either alone or in conjunction with meds. Follow up with psychiatrist for any changes in medication, additional therapies. ...Read more

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I always have a difficulty remembering specific things. Parts of movies, a plot of a book I read recently etc. Is it due to my meds, Wellbutrin/prozac?

Unsure: Impaired memory can include prob's with attention, encoding, storage, retention, and or retrieval. There are many questions yet to be asked before a doctor could give you a good answer. Other meds? Health issues? Alcohol? Cold or sleep meds? We do not usually combine wellbutrin (bupropion) and Prozac as they both inhibit P450 2D6 in the liver - sets you up for severe drug-drug interactions with other meds ...Read more

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I'm on wellbutrin (bupropion). What's the best way to add Prozac and possibly use it to replace Wellbutrin (bupropion)? What's the best med for anxiety?

I'm on wellbutrin (bupropion). What's the best way to add Prozac and possibly use it to replace Wellbutrin (bupropion)? What's the best med for anxiety?

No generral best: The issue is which one works for you individually. If Wellbutrin (bupropion) is not working consider increasing tthe dose. If that doesn't work consider adding prozac or zoloft gradually. Both can be used at same time. If your dr wants to go to one, titrate the one to stop Down while titrating the one to keep Up. Dr's supervision advised. ...Read more

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Is DEXEDRINE, prozac, and wellbutrin xl combo safe?

Not at all!: These do together with major risks between ALL! Don't just stop them but DO contact your Dr immediately and if there's any delay, find a good pharmacist to help you deal with this bad situation.
This link might show you the risks but you can search them if it fails: But best is a Dr or pharmacist: https://www. Drugs. Com/interactions-check. Php? Drug_list=843-4506, 1115-648, 440-203
Please be careful!!! ...Read more

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Is it possible to take Prozac or Zoloft with Wellbutrin?

Is it possible to take Prozac or Zoloft with Wellbutrin?

Yes: Under a physician's care, of course. In fact, Wellbutrin (an atypical antidepressant) is frequently prescribed with SSRI's or SNRI's like Prozac, Zoloft, Celexa, Cymbalta, etc. To counteract some of their side-effects and add extra anti-depressive or anti-anxiety control. ...Read more

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Is taking lithium and Prozac and wellbutrin (bupropion) ok to take adipex?

Is taking lithium and Prozac and wellbutrin (bupropion) ok to take adipex?

No: I would not recommend adipex for anyone with bipolar disorder. Lithium is often prescribed for bipolar disorder, so although you have not specifically mentioned having this problem I would be extremely wary of the possibility. ...Read more

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I've been taking Prozac 10 mg for 20 years. Lorazepam 1 mg 3 times a day. Adding Wellbutrin (bupropion) is it safe?

These meds are ok: Together. Bupropion should not be taken if history of seizures. Bupropion may increase blood levels of prozaz so your prescriber will want to know if you experience increase in side effects. Best regards for good health. ...Read more

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What's the best medication for extreme snappiness, and extremely tired very irritable. I've tried Prozac, Wellbutrin etc.?

What's the best medication for extreme snappiness, and extremely tired very irritable. I've tried Prozac, Wellbutrin etc.?

Irritable: A medication is not the only way to fix this. Please think holistically. See doc to make sure you do not have medical issues such as thyroid or other hormone imbalances. How is your diet and exercise level? Are there decisions you need to make? Consider seeing a mental health pro for support and clarification. Peace and good health. ...Read more

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Was on wellbutrin (bupropion) for a long time. Helped with anxiety/dep. Started Prozac too thinking it may help anx more, but seems to make anx worse. How is this?

Was on wellbutrin (bupropion) for a long time. Helped with anxiety/dep. Started Prozac too thinking it may help anx more, but seems to make anx worse. How is this?

Prozac (fluoxetine) causing anx?: Prozac, an SSRI, is commonly rx'ed to treat depression and anxiety d/os. Of all of the SSRIs, Prozac may b most likely 2B stimulating. Thus, it may b most likely to cause initial anxiety, which typically passes. Then we observe the meds intended effect - reduction in anxiety. All SSRIs can have this side effect. U note that u also take synthroid (thyroxine). This cld play a role. C ur doc 2 discuss next steps. ...Read more

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Would a doctor recommend adding wellbutrin (bupropion) sr to prozac?

Would a doctor recommend adding wellbutrin (bupropion) sr to prozac?

Possibly: Both are antidepressant medications with different mechanisms of action. ...Read more

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Is it safe to take Wellbutrin (bupropion), Prozac & garçinia Cambodia? Side effects?

Generally no: Prozac and Wellbutrin (bupropion) are very often prescribed together and are considered a safe and effective therapy for moderate depression and some other conditions. Garcinia, while not very well studied (a few studies have shown it to be ineffective for weight loss despite advertising), may have a similar effect on the brain as Prozac and thus can potentiate or magnify Prozac's effect in an unsafe way. ...Read more

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I'm taking wellbutrin, (bupropion) prozac, and altavera each night before bed. When I wake up, I'm always nauseous. Any tips?

I'm taking wellbutrin, (bupropion) prozac, and altavera each night before bed. When I wake up, I'm always nauseous. Any tips?

Hormones nauseate: I have found that birth control pills like altavera are much more likely to cause nausea than wellbutrin (bupropion) or prozac. Try switching to a lower dose pill, or a biphasic regimen might cause less nausea for you. Ginger root or tablets are a good fix for the nausea, we use ginger to treat the nausea of early pregnancy. ...Read more

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Can I take pain killers for a headache if I just took my Wellbutrin (bupropion) and Prozac doses an hour ago? Or should I wait?

Can I take pain killers for a headache if I just took my Wellbutrin (bupropion) and Prozac doses an hour ago? Or should I wait?

Yes, you can: After neuroimaging and physical examination have excluded structural damage of the brain, headache management depends upon the particular type of headache that is present. Then you can take your pain killer immediately to break the headache ASAP. See your PCP for more information. ...Read more

Dr. Alan Ali
789 Doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more