Top
40
Doctor insights on: Autologous

Share

Autologous (Overview)

Autologous means derived from your own body rather than from another person/donor. Often used to mean using your own red blood cells for transfusions after elective surgery or using your own stem cells for a stem cell transplant.


1

1
Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more

Autologous (Overview)

Autologous means derived from your own body rather than from another person/donor. Often used to mean using your own red blood cells for transfusions after elective surgery or using your own stem cells for a stem cell transplant.


2

2
Are stem cell transplants safe?

Are stem cell transplants safe?

Stem cells safety: Stem cell safety depends on what kind and where it is being used. Embryonic stem cells have been found to be too costly and risky for causing cancers compared to adult stem cells. Bone marrow Stem cell transplants have been used for years for cancers and is safe. see Eyedoc2020.blogspot.com for more info and safety info. ...Read more

See 2 more doctor answers
4

4
Embryonic stem cell uses?

Embryonic stem cell: Embryonic stem cell research has not shown to be as effective as adult stem cells and induced pluripotent cells. in 2009, NIH called embryonic stem cells ÔÇťobsolete" as can use adult stem cells with better results. See [email protected] for more info. ...Read more

See 2 more doctor answers
5

5
How risky are stem cell transplants?

How risky are stem cell transplants?

Stem Cells: Stem cell injections are now being used to treat painful joints (shoulders, hips, etc), Alzheimers, ALS, Lyme, Cerebral Palsy, etc. Still there are not great published studies proving its benefit in many of these conditions. We have been using limbal stem cell transplants in eye surgery for years with excellent results. See [email protected]: depends on where the stem cell is from & for. ...Read more

See 1 more doctor answer
6

6
Pancreatectomy with autologous islet cell transplantation: what does this mean?

Pancreatectomy with autologous islet cell transplantation: what does this mean?

Saving insulin: When an islet cell transplant has to be performed it means that the pancreatectomy was total. The pancreas is an exocrine (digestive juice) and endocrine gland from the Islets of Langerhans. When all are removed, islet transplant helps retain endocrine activity including insulin production. ...Read more

7

7
Does stem cell transplantation treat hematologic cancer?

Yes: Stem cell transplant is used to treat leukemias and lymphomas, both are types of hematologist malignancies. ...Read more

See 1 more doctor answer
8

8
Why are umbilical cord stem cells sometimes uses along with donor cells in an allogeneic bone marrow transplant?

Why are umbilical cord stem cells sometimes uses along with donor cells in an allogeneic bone marrow transplant?

One of the other: Stem cells can be obtained from 3 different sources: from Bone marrow of the Donor, blood of the donor or stem cells from umbilical cord. But we have to give an adequate number(Dose) of stem cells in order to have full protection. So combining them may only be needed because of inadequate number of stem cells from one of the sources ...Read more

9

9
Are bone marrow transplants painful?

Are bone marrow transplants painful?

Side effects: There are many effects which can be unpleasant like nausea, vomiting, diarrhea amd mouth sores. Depending on how the transplant is done the mouth sores can be severe and painful. There can be abdominal pain or bone pain in some patients. ...Read more

See 1 more doctor answer
10

10
Is there a centre for autologous stem cell transplantation in mumbai?

Is there a centre for autologous stem cell transplantation in mumbai?

Probably: Asia is amongst the leaders in development of adult stem cell centers and applications. ...Read more

11

11
Are stem cell transplants for multiple myeloma effective?

Are stem cell transplants for multiple myeloma effective?

Yes.: Autologous stem cells transplants (from yourself as donor when in near remission) result in improved progression free survival and probably overall survival. Allogeneic transplant (from someone else) is more complex, and many would consider it experimental. Although the procedure may cure the disease, there are significant complications and risks that may offset the benefits. ...Read more

12

12
Hi, What chances of cancer by doing Autologous Adipose derived stem cell treatment.Pls help.thanks?

Hi, What chances of cancer by doing Autologous Adipose  derived stem cell treatment.Pls help.thanks?

Not much: There isnt much but this depends on the context of why there is the transplant. It is used either in cancer http://www.wjgnet.com/1948-9366/full/v8/i2/161.htm or reconstructive surgery. In someone without cancer, they dont even do studies to evaluate risk since the risk is assumed zero. ...Read more

13

13
Is it reasonable to have second autologous stem cell transplant for myeloma?

Is it reasonable to have second autologous stem cell transplant for myeloma?

Yes: This is a very difficult question today because every situation with myeloma is different. We do not double transplant all myeloma patients like we have done in the past. It is sometimes reasonable if the first was previously successful and donor cells remain. We now have so many treatments for myeloma that sometimes we do an allogeneic transplant or treat with other drugs (velcade, carfilzomab. ...Read more

16

16
What is involved in bone marrow transplant surgery?

What is involved in bone marrow transplant surgery?

Bone marrow transpla: Bone marrow transplant is a procedure that hematologist/oncologists do for certain indication- for instance- in blood cancer like acute leukemia after remission from chemotherapy, or for certain cases of lymphomas, multiple myelomas- etc. It is not a surgery.Please read from this booklet : http://www.Lls.Org/#/resourcecenter/freeeducationmaterials/treatment/bloodmarrowstemcelltransplant. ...Read more

17

17
Will a bone marrow transplant cure bone marrow cancer?

Will a bone marrow transplant cure bone marrow cancer?

Yes: However it depends on the type of cancer, if it is in remission or not ,age of the patient and the type of donor. It also depends on the type of transplant, from self or another donor ...Read more

See 1 more doctor answer
18

18
Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or rituximab+bendamustine?

There is no: Definitive answer to your question. Studies have compared the strategies you mention. The high dose ara-c arm was closed because it was difficult to mobilize stem cells for transplant after these regimens. Bendamustine-r is a good program, and many centers would consolidate a good response with an autograft. ...Read more

19

19
What is bone marrow transplant used for?

What is bone marrow transplant used for?

Certain cancers: Blood stem cell or bone marrow transplantation is used to treat certain hematologic malignancies (blood cancers) such as leukemia. They can also be used for bone marrow failure, certain hemoblglobin disorders such as sickle cell anemia, and some genetic disorders. ...Read more

20

20
What is the definition or description of: autologous?

What is the definition or description of: autologous?

Autologous: Autologous means derived from your own body rather than from another person/donor. Often used to mean using your own red blood cells for transfusions after elective surgery or using your own stem cells for a stem cell transplant. ...Read more

22

22
Hi doctors, was just wondering what is autologous transfusions?

Hi doctors, was just wondering what is autologous transfusions?

Self transfusion: In certain preoperative situations where it is expected that there could be a significant amount of blood loss and the blood type not that common, the patient is asked to be his own donor. This is not used where there is an acute situation but rather for an elective procedure. Here in one or two instances the patient donates blood to be stored for his own procedure while count returns to normal. ...Read more

23

23
How long does it take to recover from autologous chondrocyte implantation?

How long does it take to recover from autologous chondrocyte implantation?

ACI: It take about4-6 weeks to recover from the procedure and for the healing and show result 6month to 2 years. ...Read more

See 1 more doctor answer
24

24
Is it safer to do autologous transfusion for hysterectomy?

Yes: Even though blood is tested thoroughly to prevent the passage of disease to the patient, nothing is safer than your own blood. ...Read more

See 1 more doctor answer
25

25
I have lcdd and mm. I had done an autologous transplant 18 months ago and now i need to have valcade for 3-6 months. What are my chances of recovery?

I am not sure what: Lcdd is, but the fact that you are being recommended for further treatment 18 months after an autograft suggests the mm is progressing at least in terms of what can be measured in the laboratory. There are many post transplant treatment strategies in mm, but specifics relative to your personal prognosis can not be extrapolated from the information given. ...Read more

26

26
Pancreatectomy with autologous islet cell transplantation: what does this mean?

Saving insulin: When an islet cell transplant has to be performed it means that the pancreatectomy was total. The pancreas is an exocrine (digestive juice) and endocrine gland from the Islets of Langerhans. When all are removed, islet transplant helps retain endocrine activity including insulin production. ...Read more

27

27
Can you tell me about pancreatectomy with autologous islet cell transplantation?

Total pancreas out: Most of the islet cells that produce glucagon and insulin are in the body and distal pancreas so that to have them removed requires a total pancreatectomy. Autologous transplants are being performed at the present time by Dr.Horatio Rilo but if not perfomed. hormone replacement required as wll as pancratin for digestion. ...Read more

28

28
Artificial Tears and Autologous serum (AS) tears are different right? How are they different? Is one newer? Is one better? Advantages/disadvantages?

Artificial Tears and Autologous serum (AS) tears are different right? How are they different? Is one newer? Is one better? Advantages/disadvantages?

Quite different: Artificial tears are commercial products that substitute for tears. Autologous tears are a mixture of an artificial tear and the serum from your own bloodstream. They usually are superior but are reserved for more severe cases poorly responsive to regular tear drops. They have to be made in compounding pharmacies and are quite expensive. But can be of great help for those who need them. ...Read more

See 1 more doctor answer
29

29
When and how was autologous blood donation and transfusion started?

When and how was autologous blood donation and transfusion started?

Likely 20th century.: The era of modern blood transfusion likely started in 1901, when the austrian karl landsteiner discovered human blood groups and made them safer. The first non-direct transfusion was done on march 27, 1914 by the belgian doctor albert hustin, though this was a diluted solution of blood. Since then many improvements were made to result in the modern system of today, including autologous methods. ...Read more

30

30
Is there any evidence to show that placental stem cells are more beneficial than autologous stem cells? Specifically for fixing orthopedic problems

Placental stem cells: I did some search, how where I was unable to find any paper in which there is a discussion comparing the benefit of placental stem cells vs. than autologous stem cells. In most cases stem cells are procured from the umbilical cord, in many institutions in which bone marrow transplantation is performed, the institution keeps HLA mapping as well as haplotypes. Is quite possible, that in the future ...Read more

31

31
My husband has relapse systemic and CNS dlc lymphoma. His family history has a lot of cancer. Would it be better to do more dhap or autologous hsct?

My husband has relapse systemic and CNS dlc lymphoma. His family history has a lot of cancer. Would it be better to do more dhap or autologous hsct?

Speak with your MD: This is very complicated. If he can get into remission with systemic chemotherapy and intrathecal chemotherapy, a stem cell transplant might be indicated. In the meanwhile, additional chemotherapy could include dhap. Please speak with your oncologist to get the best advice. ...Read more

32

32
Is there a centre for autologous stem cell transplantation in mumbai?

Probably: Asia is amongst the leaders in development of adult stem cell centers and applications. ...Read more

33

33
What is an autologous stem cell transplant and am I a candidate for one?

What is an autologous stem cell transplant and am I a candidate for one?

Means of treatment: In some cases, the best way to treat the disease, especially if it has come back after initial treatment is to use doses of chemotherapy or radiation which is high enough to destroy normal bone marrow cells. To "rescue" these cells, they are stimulated with drugs before high dose therapy that cause very immature cells called stem cells to enter the blood where they can be collected and given back. ...Read more

See 1 more doctor answer
34

34
What is a autologous bone marrow transplant?

The patient is donor: In case of myeloma certain lymphomas in general patients receive chemotherapy , achieve a response and then have stem cells mobilized from their marrow- frozen- patient goes through high doses of chemo to clear the marrow or kill as many tumor cells as possible and then reinfuse cells back. The idea is that high doses of chemotherapy can cause prolong remission or cure ...Read more

See 2 more doctor answers
35

35
How long does the autologous bone marrow transplantation take?

About 4-6 weeks: There are 2 steps- the first is to collect your stem cells which usually is a 5-15 day process. Then the next step is the transplant phase which usually involves about a week of therapy, then getting your own saved cells thawed and infused back to you like a blood transfusion (over an hour for instance), then 2-4 weeks of recovery. ...Read more

36

36
What is an autologous bone marrow transplant and when is it used?

What is an autologous bone marrow transplant and when is it used?

High dose chemo: This is a treatment that uses very high doses of chemotherapy and/or radiation to treat cancers. The doses are so high that the normal bone marrow is destroyed. The patient's own bone marrow or stem cells are then reinfused to allow the bone marrow to recover. It is used for certain cancers and some autoimmune diseases. ...Read more

See 1 more doctor answer
37

37
I am going to have an autologous stem cell transplant what is my survival rate?

I am going to have an autologous stem cell transplant what is my survival rate?

About 97%: In a standard risk situation only 2-3% of patients die from complications related to the transplant. The intermediate and long term survival is a function of the underlying disease and thus comment is not possible without the entire clinical context. ...Read more

38

38
What is the goal/ predicted outcome of autologous stem cell transplantation studies for ms?

What is the goal/ predicted outcome of autologous stem cell transplantation studies for ms?

Multiple sclerosis : Researchers are optimistic. Yet, no proven efficacy as of yet. Mortality is down to 1-2%. Check following site: http://www.Ncbi.Nlm.Nih.Gov/m/pubmed/18565456/. ...Read more

See 1 more doctor answer
39

39
Cousin is 64 with stage 4 Mult Myel. Had Autologous stem cell trans 4 months ago..Why would Dr put him on a light chemo pill now.Are cancer cells back?

Cousin is 64 with stage 4 Mult Myel. Had Autologous stem cell trans 4 months ago..Why would Dr put him on a light chemo pill now.Are cancer cells back?

Not necessarily: Maintenance chemotherapy is recommended to keep the tumor cells from coming back. Tumors cells are usually not eliminated by the treatment your cousin had, but may be kept in check by the treatment being prescribed. ...Read more

40

40
Is it reasonable to have second autologous stem cell transplant for myeloma?

Yes: This is a very difficult question today because every situation with myeloma is different. We do not double transplant all myeloma patients like we have done in the past. It is sometimes reasonable if the first was previously successful and donor cells remain. We now have so many treatments for myeloma that sometimes we do an allogeneic transplant or treat with other drugs (velcade, carfilzomab. ...Read more