4 functions of cell membrane

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How is the sickle cell trait passed on?

Straightforward

Sickle_cell_anemia
The beta globin gene is on chromosome 11. Everyone has two, one from each parent. If you have sickle trait, one is normal and the other has the sickle mutation. Half your germ cells (eggs or sperm) will carry the normal gene, half the mutated gene. If you give the mutated gene to your child, they have sickle trait. If they get a mutated gene from your partner too, they have sickle cell disease.
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What causes the sickle cell trait?

It is inherited

Sickle_cell_anemia
Hemoglobin (hgb) is a complicated chemical that is in the red blood cells and carries oxygen. We inherit one gene from each parent that makes one of the parts of hgb called beta chains. If we inherit a sickle beta chain gene from one parent and a normal beta chain gene from the other, we have sickle trait. If we inherit a sickle beta chain gene from both parents, we have sickle cell anemia.
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What is stem cell transplantation used for now?

Certain cancers

Blood
Blood stem cell or bone marrow transplantation is used to treat certain hematologic malignancies (blood cancers) such as leukemia. They can also be used for bone marrow failure, certain hemoblglobin disorders such as sickle cell anemia, and some genetic disorders.
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What is sickle cell trait and anemia?

Genes

Blood
Sickle cell anemia occurs when someone has 2 sickle cell genes. Normal hemoglobin (HB) genes code for HB A. A sickle cell gene codes for HB S. Having 1 HB A gene & 1 HB S gene leads to sickle trait. This will have no symptoms, but has some health consequences. 2 genes for HB S leads to sickle cell anemia. To make things more complicated, there are other abnormal HB genes that can cause problems.
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Dr. Karl Muench answered:

is there a cure for sickle cell trait?

No

Sickle_cell_anemia
And no cure is needed. With rare exceptions sickle trait has no impact on health and longevity.
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I was wondering what are the risks of the sickle cell trait?

Check this out:

Sickle_cell_carrier
http://www.cdc.gov/ncbddd/sicklecell/documents/SCD%20factsheet_Sickle%20Cell%20Trait.pdf
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What is the cause of sickle cell trait?

It is inherited

Sickle_cell_anemia
Hemoglobin (hgb) is a complicated chemical that is in the red blood cells and carries oxygen. We inherit one gene from each parent that makes one of the parts of hgb called beta chains. If we inherit a sickle beta chain gene from one parent and a normal beta chain gene from the other, we have sickle trait. If we inherit a sickle beta chain gene from both parents, we have sickle cell anemia.
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Dr. Scott J. Diede answered:

Please help? Is the sickle cell trait deadly?

No

Sickle_cell_carrier
The vast majority of patients with sickle cell trait have no health consequences whatsoever.
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Dr. Scott J. Diede answered:

Could a the sickle cell trait skip generations?

No

Sickle_cell_carrier
Sickle cell trait is when a person has one mutated copy of the beta-hemoglobin gene and one normal copy. You always inherit the mutated hemoglobin from one of your parents. Thus, one parent always has at least sickle cell trait if the child has sickle cell trait. Therefore trait does not skip a generation.
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Are there stem cell transplantation therapy trials in the U.S.?

Yes

Liposuction
Use of adult mesenchymal stem-stromal cells (MSCs) are currently in clinical trial in US/Internationally. Trend is toward use of fat derived MSCs, havested by liposuction, isolated and concentrated in tissue culture. Early reports suggest significant improvement in neurological, autoimmune and organ functions. Many more MSCs in fat than bone marrow making AD-MSC the center of most research now
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