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Doctor insights on: 2nd Trimester Blood Screening

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I had a normal first trimester screening and harmony prenatal test. Is an AFP blood test necessary? Can it come back high risk?

I had a normal first trimester screening and harmony prenatal test.  Is an AFP blood test necessary?  Can it come back high risk?

The msAFP is: To assess the risk of open neural tube defects i.e. Spina bifida, which is not tested by harmony or the first trimester screen. It is up to you if you would like to be screened for ntds. Keep in mind that, if detected, these defects can be repaired by a skilled pediatric neurosurgeon while the baby is still inside you. Speak to your obgyn and make an informed decision. Hope this helps. ...Read more

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Dr. Ronald Krauser
1 doctor shared a insight

Screening (Definition)

Examples are: colonoscopy for colon polyp or cancer; mammograms for breast lesions or cancer; psa a blood test that could indicate enlargement of cancerous prostate tissue; blood sugar or hemoglobin a!c for diabetes. Many think that scanning the whole body will pick up a cancer--in all likelihood, it will not. There also is no good blood test, yet, ...Read more


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What are some reasons for a second trimester miscarriage beside chromosomes, blood clotting, uterine issues, and autoimmune?

What are some reasons for a second trimester miscarriage beside chromosomes, blood clotting, uterine issues, and autoimmune?

That is most: Another cause could be an incompetent cervix, anesthesia or radiation exposure or other toxin exposure. If this is a repetitive thing for you, you should see a specialist who can work you up for potential causes and treat them. ...Read more

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I am in mid second trimester. My TSH level in this stage is 6.03 the limit is 0.4 to 5.5. Will there be any problem. I gave my blood sample in fastin (phentermine)?

I am in mid second trimester.  My TSH level in this stage is 6.03 the limit is 0.4 to 5.5. Will there be any problem. I gave my blood sample in fastin (phentermine)?

TSH too high: Because of the physiologic hormone changes that occur during pregnancy, the TSH typically goes down. During the second trimester, TSH should typically be. ...Read more

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What is a first trimester screening for a fetus?

What is a first trimester screening for a fetus?

Blood and U/S tests.: First trimester screen for any pregnancy includes a sonographic examination to determine plurality, basic fetal anatomy, gestational sac location, fetal viability and gestational dates - as well as blood tests (hcg, papp-a, maternit21/harmony tests) to determine the risk for down syndrome, fetal growth restriction, preeclampsia (uterine artery dopplers), preterm birth (cervical length). Nicolaides. ...Read more

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What is first trimester screening and maternal fetal medicine?

What is first trimester screening and maternal fetal medicine?

Ob terms: 1st trimester screening are any tests done during a pregnancy during the first 12-14 weeks of pregnancy. This can include ultrasounds. blood tests and others. Maternal fetal medicine is a subspecialty of obstetrics. It's also often called "perinatology". These are obstetricians who go on to do additional training in the management of high risk pregnancies. ...Read more

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If the 1st trimester screening for Down syndrome was negative, how much does an echogenic focus at 20 week screening factor in?

If the 1st trimester screening for Down syndrome was negative,  how much does an echogenic focus at 20 week screening factor in?

Amniocentesis is key: If you had amniocentesis which did not reveal abnormalities consistent with .Down syndrome, then the only concern would be structural abnormalities, such as heart abnormalities. If you have not had amniocentesis, you should have it. ...Read more

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Should i be worried if soft markers were found in anatomy scan when harmony, AFP and first trimester screening were very low risk?

I'm sure it's hard : Not to worry till your OB can gather enough additional information to confirm or rule out a problem. However, it also assures you that you & your baby are receiving excellent medical care & that all needed tests &/or referrals will be offered to you in a timely fashion. Try to stay positive & healthy. You may not have. Been able to process everything your OB said at first, so ask him/her again. ...Read more

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Already had harmony test, afp, first trimester screening and they were all very low what might a dr suggest if soft markers are found on anatomy scan?

Already had harmony test, afp, first trimester screening and they were all very low what might a dr suggest if soft markers are found on anatomy scan?

Reassurance!: If all that's found is a soft marker, and your screening and cell free dna results are normal, the most likely answer is that the soft marker is a normal variant. However if there is a finding consistent with a birth defect, that might merit further investigation, such as diagnostic testing within amniocentesis. ...Read more

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Which is a better predictor of Down syndrome during the first trimester screening, low papp-a or high hCG levels? Or the ratio between the two values?

Which is a better predictor of Down syndrome during the first trimester screening, low papp-a or high hCG levels? Or the ratio between the two values?

Four tests: A combination of four tests, quad screen, is done twice as a screening test for down syndrome. See this site for more info. http://www.mayoclinic.com/health/quad-screen/my00127. ...Read more

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Fetal hb @ 6w2d. Doc didn't tell me # of BPM & i didn't ask but was only told to come back @ 12w to have the 1st trimester screening. Shoud i worry?

Fetal hb @ 6w2d. Doc didn't tell me # of BPM & i didn't ask but was only told to come back @ 12w to have the 1st trimester screening. Shoud i worry?

No: The presence of the heart beat is way more significant than the exact rate and the chances of miscarriage are much decreased. Your doctor would certainly be bringing you back sooner if the rate was not in a normal range. ...Read more

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My 1st trimester screening came back very low 1 in 3, 000. I just took the harmony genetic test. Is there any chance my risk can change to high risk?

My 1st trimester screening came back very low 1 in 3, 000. I just took the harmony genetic test. Is there any chance my risk can change to high risk?

Not likely: Your numbers are quite good. The 1 in 3000 is based on your first trimester screen which is a probability. The harmony test is based on the fetal dna in your blood. Therefore, it has a higher detection rate than the first trimester screen, and in theory could change--but not highly likely given your good numbers. ...Read more

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What testing is done in 2nd trimester?

What testing is done in 2nd trimester?

Variable: Maternal serum screen (afp4 or 5), fetal anatomy survey, 1- hour gct (glucose challenge test), etc... Check out text4baby. Good resource. ...Read more

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How serious is a 2nd trimester miscarraige?

How serious is a 2nd trimester miscarraige?

No fun.: A second (mid-)trimester pregnancy loss is a painful and potentially dangerous complication. Seek expert care with gynecologists trained to perform d&e and midtrimester terminations. ...Read more

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What happens during 2nd trimester abortion?

What happens during 2nd trimester abortion?

Uterine evacuation.: Surgical or medical/mechanical methods can be used to empty the gravid uterus in the second trimester. The earlier one decides to terminate a pregnancy the safer, less costly, less traumatizing and faster it is. Consult with your gynecologist for additional details. ...Read more

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If CF could you pass the blood screening and not the sweat test?

If CF could you pass the blood screening and not the sweat test?

Yes: Depending on what "blood screening" you are referring to, overall, the answer is yes. A screening test is designed to pick up most cases of a disease, but some do fail to be picked up. The sweat chloride test is considered the gold standard test for cf. ...Read more

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Exactly when did bloodbanks start screening blood for hepatitis b?

Exactly when did bloodbanks start screening blood for hepatitis b?

Early 1970s: Hbv was diagnosed in the later 1960s. By 1971, testing was being done using the surface antige (hbsag). The core antibody was added in 1986 and by 2009, nucleic acid testing was used. The risk of hbv through blood transfusion is now between 1 in 200, 000 and 1 in 500, 000 units of blood. ...Read more

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Is it safe to take dyphenhydramine n psuedoepihdrine in 2nd trimester for flu?

Is it safe to take dyphenhydramine n psuedoepihdrine in 2nd trimester for flu?

Know this site: http://www.drugs.com/pregnancy-categories.html. It is classified as Pregnancy Risk Class B, ie there has been no evidence of associated risk & is generally considered not to be harmful to the unborn fetus. It doesn't cross over the maternal-fetal boundary of the placenta. That said, it is secreted into breast milk & is considered unsafe for newborns once outside of the womb due to excess sedation. ...Read more

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Could blood be screened for cancer cells even if the screening is not always reliable?

Could blood be screened for cancer cells even if the screening is not always reliable?

Yes/No: Cancer may or may not show in the blood. If one has blood cancer(leukemia) then it will show in the blood. Most other cancers(Solid tumors) do circulate some Cancer cells but they are difficult to see in routine blood testing. Circulating tumor cells and more recently DNA fragments from cancer cells are under intense research study. You have to go to a major Cancer Center to have this test done. ...Read more

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Please tell me how long it takes for to get blood screening results back to check for any signs of cancer?

Please tell me how long it takes for to get blood screening results back to check for any signs of cancer?

Depends on the test: Except for leukemias, blood tests are usually not diagnostic of cancers. Results of blood tests for leukemia may take anywhere from one day to a couple of weeks depending on the investigations needed. ...Read more