Doctor insights on:
17 Hydroxypregnenolone Baseline
My son-14 5/12, 5'3",pubertal changes,bone age-13.5y, GH stim test peak-7.6, IGFI-332, IGF-BP3.LC-3916, NL-T4free,Testost,TSH
How could free testosterone measured by equilibrium dialysis (mayo labs) be over 50% more than calculated free testosterone (issam.Ch)? Data (4/26): tt 533, shbg 41, albumin 4.5, cft 9.7, ft 15
Lab variation: The calculated free t will depend on how accurately the lab measures each component (total t, shbg, albumin) as well as the algorithm used to do the calculation. The free t by dialysis can be more accurate, as it depends on one test being done correctly. However, labs vary enormously in how well and accurately they can do the test. If the levels are normal, don't fret the details. ...Read moreSee 1 more doctor answer
FSH=4.5, LH=5.3, Progesteron=1.5, Testosterone=0.5, SHB Glob=46, Test/SHBG ratio=1.1, Prolactin=110, 17 bet OST=145. Test taken after menses, Normal?
5/2012 3TIA/shock 68/45/mottling/flushing/tinn/MCA 4/2013 Daily HypCrisis HR 48-147 PP 18-22 CerebAneurysm Tbthk sput visible blaschko acrocyanosis +ppl lips/tong Orthypnea Afib Glob Hypoxic injury?
Multiple conditions: Your cardiologist and neurologist are your main sources of help. There are signs of thromboembolism related to atrial fibrillation. Hopefully there is no signs of cerebral impairment- weakness on one side, forgetfulness, slurred speech etc. U need help from ancillary services- physical/speech therapy, rehab etc we need serious help from the supreme being! god bless u! ...Read moreSee 2 more doctor answers
FSH=4.5, LH=5.3, Progesteron=1.5, Testosterone=0.5, SHB Glob=46, Test/SHBG ratio=1.1, Prolactin=110 Miu/L, 17 bet OST=145. Test after menses, Normal?
What is the true normal AFP level? The lab ref says <8 ng/ml, but mayo clinic says non-pregnant level 0.2 ng/ml (& peak @32wks to 250 ng/ml).
A subtle key concept: You ask an excellent question. There is no "true normal" alpha-fetoprotein level any more than there is a simple number for "too fat" or "too tall." a reference range is not a "healthy range"; it is merely a range in which most but not all healthy individuals fall. The key is "decision levels" -- what would I do if my AFP was 1.2 ng/ml? I'll bet nothing, unless it was as a recurrent marker. ...Read more
Recently had pituitary surgery. Current cortisol levels bl 4.1, 30 min a/i 18.6, acth plasma level 6. All numbers seem low, dr said norm. Second opin?
Don't know enough: About your case to be specific. I assume the "a/i" is after syncortropin injection, which is an appropriate response, but only checks your adrenal glands. Cortisol and acth are slightly low but not dangerously so. I would discuss your concerns with your doctor. ...Read more
Laparoscopy 8/3, stage 1 endo. Elevated prolactin levels, parlodel (bromocriptine) 2.5mg 3X week. How long for levels to drop and conceive? Thanks!
Acth Stimulation test:
PRG 17-0H basal: 3.70nmol/l
30min interval: 9.83nmol/l
60min interval: 12nmol/l
Heterozygous or Homozygous NCAH? Or Pcos?
NCAH or PCOS?: Not nonclassic adrenal hyperplasia with early morning 17-OH progesterone less than 200ng/dl. Yours, with conversion is 122ng/dl. Also, your stimulated level doesn't reach higher than 400ng/L. That means no 21-hydroxylase or 11beta-hydroxylase or 3-beta-hydroxysteroid dehydrogenase or 17-alpha-hydroxylase deficiency. PCOS. ...Read more
45yo, day 11 menstrual: serum shgb 144.1(range 24-122); %free testos 0.5(range 0.8-1.4); cortisol 4.5 (8am range 8-19) ;estradiol 122(range follicular 30-100); basic thyroid look norm. Any sig here?
ACTH challenge done10am, baseline ACTH less than 5, cortisol is at 8 (mayo range) symptoms of Adrenal fatigue, Autoimmune, pots. Tests still needed?
What test?: Are you asking whether the ACTH challenge is needed after it has been done? This is best discussed with your endocrinologist who can explain to you the rationale behind his request. ...Read more
10:58 min sec achieving 86 %
FAC, Peak heart rate was 181 BPM,The patient achieved 12.0 METS, how accurate is a stress echo with these stats? negative
On levothynxine .025 mcg. Normal thyroid. 433.8urine calcium- 1800 ml urine sample.Bd -0.9rt hip/neck. -0.8 lumbar. -0.4 forearm. Meaning? Recommendat
Questions: http://www.jbc.org/content/28/1/237.full.pdf to better understand that urinary calcium levels vary. It is best to do a creatinine clearance and a 24 hour urinary calcium level. Whoever ordered it should review it with you. The thyroid function is ok so you should stay on that dose. The bone density is more accurate in hips and lumbar spine and should be reviewed with your doc. ...Read moreSee 1 more doctor answer
Can ACTH test rule out Cushing's? ACTH stim. Cortisol levels: T0: 9.1 T30: 16.6 and T60min: 18.6. Should I have 24 hr cortisol levels checked?
Wrong test: Hi. The ACTH-stim test is not a test for Cushing's. It's a test for adrenal insufficiency, more exactly, PRIMARY adrenal insufficiency. So no, an ACTH-stim test cannot rule out Cushing's. Someone needs to suspect you of Cushing's to order the 24h urine cortisol. We don't have any info to make us suspect Cushing's in you, so we can't say if you SHOULD have a 24h urine cortisol. Your ACTH-stim is nl ...Read more
36 y/o female runner c/o fatigue. Cbc, cmp, tsh, t3, (liothyronine) t4, mg, b12, folate, vit. D level 140 ng/ml. Not on supplements. Asymptomatic. How to proceed?
Runner fatigue: That vit d level is high. Could this be from running outdoors (i.e. Sun exposure), or supplements? I am thinking the latter. You may want to question her about this. How thin is she? How much running? If she's having normal periods, then probably not hypothalamic. If she's an extreme runner, she may need to detrain briefly, but good luck trying to persuade her. ...Read moreSee 3 more doctor answers
Follow-up endo appt on 3/4, what to ask? Test results-serum testosterone 204, lh-2.5, fsh-6.6, estradiol-18.1, dhea-92.6. Hypothyroid, 5'10", 275lbs.
Im 39 years male with 2nd degree infertility. result shows: LH 5iu/l, FSH 5IU/l, Prolactin 0.8nmoi/c, total testosterone 15.60 nmol/l. is this normal?
No. All of these: values are quite low. It suggests the problem may be in the realm of the pituitary gland which produces the hormones--LH (luteinizing hormone) and FSH (follicle stimulating hormone) which stimulate testosterone production. The low prolactin also suggests this. You will likely need a specialty consultation with an Endocrinologist. Good wishes:) ...Read more
Variable: 17-hydroxypregnenolone children* males premature (26-28 weeks): 1, 219-9, 799 ng/dl premature (29-36 weeks): 346-8, 911 ng/dl full term (1-5 months): 229-3, 104 ng/dl 6 months-364 days: 221-1, 981 ng/dl 1-2 years: 35-712 ng/dl 3-6 years: <277 ng/dl 7-9 years: <188 ng/dl 10-12 years: <393 ng/dl 13-15 years: 35-465 ng/dl 16-17 years: 32-478 ng/dl adults males > or =18 years: 55-455 ng/dl. ...Read more
No 21OH-ase defect: 17 hydroxyprogesterone screens for a congenital condition, congenital adrenal hypertrophy (cah) which can lead to abnormalities of normal cortisol production and excessive adrenal male hormone production. These can present at birth, in childhood, adolescence, or adulthood depending on the nature and severity of the defect. The sensitivity of the baseline test can be increased with acth stimulation. ...Read more
Satisfaction...: ...That you have taken a proactive step to check for breast cancer before it is palpable, significantly increasing your chance for cure. Mammograms are screening tests, meaning that they will find many "false alarms" at the expense of not missing cancers. As often as 5-10% of the time, you will be asked to come back for a closer look, ultrasound, etc--don't be alarmed--better safe than... ...Read moreSee 2 more doctor answers
A dood idea: Do not apply deodorant that day. The test takes only a few minutes but leave yourself an hour or longer for the paper work and if they had to do more images. Some patients experience some discomfort with the mammogram. But most do not. You should be able to resume your usual activities afterwards. If you don't receive your results in 2-3 weeks call and inquire. Also schedule a clinical breast exam. ...Read moreSee 2 more doctor answers
When is it appropriate to test hormone levels for 52 yr old female? Is it important to establish baseline?
Rarely needed: There are a few very specific situations in which testing hormone levels could be helpful. But most often we want to make sure of helping the woman feel better regardless of what the numbers show. Baseline levels aren't needed. http://www.cascadewomenshealth.org/download/pdfs/healtheducation/menopausal%20management/paced-breathing.pdf. ...Read more
I understand the pill itself excretes quickly but how many cycles until bleeding and moods return to baseline?
By the next cycle : Or the one after that at the latest, if it isn't normal see your gyn or a workup. ...Read more
Use travatan z for 2 weeks. Baseline pressure is 28. Pressure reading today is 16. Can 1 drop lower pressure that many points?
Encouraging: Travatan may on average lower the pressure by 30%. This however is only the average and so some eye will respond better. Since the eye pressure varies throughout the day and is affected by many factors, more than one measurement will be required to determine whether the pressure is (a) definitely at this level (b) together with other testing, has resulted in satisfactory treatment of glaucoma. ...Read moreSee 1 more doctor answer
Acth stim test done. Acth was 12 at baseline cortisol 1. At 30 minutes cortisol was 22.7 then 1hr at 29. Does this indicate secondary ai?
Adrenal insuff: The results of the acth stim test suggest that ai is not an issue. The cortisol level responded as expected to the stimulation. If at the start of the test, you were ill then it might suggest that you have a relative ai as your initial cortisol level was 1 (ok if your healthy and not stressed, but in an ill person the cortisol should be higher in response to stress). ...Read more
ACTH stim test...I've seen so many reference ranges I don't know how to interpret mine with 12.8 baseline, 20.4 @ 30 and 21.1 @ 60 minutes?
My son seems crankier after he gets his vaccinations. Is this normal? It's seems to take a week before he is back to baseline in terms of mood
I have POTS syndrome& my baseline catecholamine levels are quite abnormally low & did't respond to the catecholamine injection. Normal with POTS?
Depends: The good news is most people with POTS due well over time. The frustrating part is that it is possibly more than one disorder with similar symptoms. The diagnosis is relatively straightforward & usually done with a tilt table test. What exactly you are referring to as a catecholamine injection could be a variety of things & are rarely done. Confirm diagnosis & see someone specializing in this! ...Read more
Acth stim test showed baseline of 17, rising to 33 43mins later. borderline and maybe a secondary adrenal issue, or just normal? symptoms for years.
If mean cortisol,,,,: If you're talking about cortisol levels rising from 17 to 33 ug/dL on under 60 min is a normal reaction after being stimulated with ACTH, however, the values are low which could signify a primary adrenal issue, like Addison's disease, or something less like an under functioning adrenal. This would likely require hormone replacement therapy if this was the case so see your Dr. for more details. ...Read more
Acth stim test.My baseline cortisol was 17.5. After 30 min, cortisol =22. After 60 min, =26.I thought cortisol should raise 20pts but i was told normal.?
Perhaps: In healthy individuals, the morning cortisol level should double from a baseline of 20-30 µg/dl within 60 minutes. The baseline cortisol level in people with adrenal insufficiency is usually below 15 µg/dl. An acth stimulation test that raises the cortisol concentration to 20 µg/dl would support the diagnosis. Make sure you have the right units. ...Read more
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