Doctor insights on:
126 Creatinine Urine
Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more
Not much: Urine creatinine is concentrated with dehydration, but is always higher than blood creatinine except in severe kidney desease. The urine creatinine is much higher than blood in a normal state. The importance of urine creatinine is in the calculation of creatinine clearance and fractional excretions. This requires interpretation by your physician. ...Read more
Urine creatinine: Our corresondent is talking about urine creatinine. This may be high because the urine is concentrated (i.e., the person drank little water) or the person is well-muscled. It's not a cause of concern. ...Read more
No cause for concern: Usually it means you are well-muscled or just big. ...Read more
I recently had a creatinine urine 24hr test which came out high (2100 mg/24hr). What does this generally signal?
You're fine: Especially if you're a bit more muscular than today's average guy, or a big guy, or you drank a lot of water that day, or it's actually a few more than 24 hours, or you ate an extra serving of meat, i'd consider this normal. The only value in measuring it is to give other substances "per gram of creatinine". ...Read more
No such thing: We don't publish a reference range as people would worry. The more muscle mass you have, the more creatinine you put out daily. The level in turn is also a function of how much water you drink -- whether the urine is concentrated or dilute. And there's no illness for which increased or decreased production is a marker. If you do find a published range, ignore it. ...Read more
Absolutely nothing: You're probably not a female bodybuilder and you drank a little extra water. I'm glad I could reassure you. ...Read more
No: There must be a misunderstanding. I'm sorry for the confusion. ...Read more
Dehydration: It appears that you may have dehyrdated cauisng hypernatremic (hypertonic) dehydration. This occurs when the lost fluid contains less sodium than the blood (loss of hypotonic fluid). Relatively less sodium than water is lost. Please be sure blood glucose, sodium and chloride levels were normal. I would see your doctor and have the urine test repeated along with a urinary sodium level. ...Read more
Yes: Urine creatinine means nothing in any case. It's secreted at a constant rate in proportion to your muscularity. It's merely a reference value to which you compare other analytes. ...Read more
For muscularity assessment, does creatinine measurement has to be made always in 24 h collected urine?
Not related: You do not need to measure urine creatinine to assess muscularity. ...Read more
My Creatinine urine level went from 73 to 20 in 4 mons BP high, 201/112 yesterday. Pluse 136. What can b wrong w/me. No med changes, should I worry?
Yes: You need medical care as soon as possible. ...Read more
How to keep creatinine levels above 20 mg/dl? I do not use drugs but need a drug urine test 3 times a week. The level of creatinine must be over 20 mg/dl. I changed nothing in my diet and recently had a level of 14.1 and was told I diluted. I am worrie
The most common reason for low creatinine is that you drink a lot of fluids. It is not abnormal to have low creatinine, it's just that the people doing the lab test want the urine concentrated enough that it can pick up trace amounts of the drugs they are testing for. Dilute urine= less of drug in urine sample. Some people have a medical condition that makes them unable to concentrate their urine (low levels of adh (vasopressin), (vasopressin) anti-diuretic hormone) release from the pituitary gland.
If you don't have this condition, then on test days avoid liquids (sips ok, glasses not ok) until after the urine test. Best results would be to avoid liquids 4 hours before test. If creatinine is still low, you might want to see an endocrinologist to evaluate for low adh (vasopressin). If the doctor can validate this, then your employer can't legally hassle you about your low creatinine. ...Read more
Tell kidney function: Single urine specimens can be tested for creatinine. But daily urine output and urinary concentration varies hence a 24 hr urine collection. Normal creatinine output for an adult should be >1gm/24 hours. Also getting blood creatinine provides optimal way to accurately determine creatine clearance which in turn is a most accurate way to measure kidney function. ...Read more
Likely no problem.: Your creatinine is within normal range (< 1.5 mg/dl). Normal ranges can vary, but this is well within many. Your 24 urine was normal, which likely means your kidneys are working properly and you likely don't have any diseases, like diabetes, etc. That cause abnormal amounts of urine to be produced. ...Read more
See below: On a random spot, unlke on a 24 hour urine collection, urine sample, urine creatinine excretion is measured. ...Read more
Not reabsorbed: Creatinine is used to calculate glomerular filtration rates because the kidney does not reabsorb it: whatever gets filtered into the glomerulus ends up in the urine. So it is a reliable indicator of how much blood has been filtered. All you have to calculate is the volume of blood that contained the amount of creatinine that appeared in the urine over a certain time. ...Read more
Strong kidneys!: It sounds like your kidneys are working normally. That's what they're supposed to do -- clear metabolic products like creatinine from the blood, dumping it into the urine. The urine level might be especially high if you haven't been drinking lots of fluids lately, i.e. if the urine is relatively concentrated. In any case, this is a good sign, nothing to worry about. ...Read more
Dear dr. My greandfather is 88 yrs old his urine creatinine is 4.7 so it's need to do kendy dialysis?
Likely: Ifnot now he is getting close.Get a more detailed answer ›