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Doctor insights on: 12 Weeks Of Taxol Herceptin How Bad Is It

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What are side effects of low dose taxol with herceptin every week for 12 weeks i have stage 4 kidney disease and am concerned?

What are side effects of low dose taxol with herceptin every week for 12 weeks i have stage 4 kidney disease and am concerned?

Yes, but...: Has your stage-4 kidney disease occurred before or after Herceptin with low dose of taxol? Herceptin is known to have significant adverse effects on to the kidneys and Taxol is not. So, it is good idea to ask your treating doctor for the specific profile possibly fitting you since s/he knows more about you than anyone online and will monitor your kidney function while receiving Herceptin. Best.... ...Read more

Dr. Tanya Russo
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Trastuzumab (Definition)

Trastuzumab is an antibody based agent which is a kind of ...Read more


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Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?

Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?

Yes: You have obviously survived the bilateral pulmonary emboli. You didn't mention being on Coumadin (warfarin) or any blood thinner but you should be if you are not(speak to your doctor). Hopefully, most of the clot on your lungs has dissolved. If you can't be on blood thinners for some reason, you could have a filter placed in your vena cava. Having cancer is a risk factor for having blood clots and pes. ...Read more

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Want to stay on herceptin (trastuzumab) and switch from Taxol to gemzar. What is the difference?

Want to stay on herceptin (trastuzumab) and switch from Taxol to gemzar.  What is the difference?

Less neuropathy: Unlike taxol, (paclitaxel) gemcitabine does not cause neuropathy. It can cause low platelets. It can also cause fluid retention. Also it is usually given 2 weeks on and 1 week off. Unlike Taxol (paclitaxel) which typically is given weekly. That is about it in regards to the difference. Hope this helps. ...Read more

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Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read more

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What is the half life of taxol & carboplastin?

What is the half life of taxol & carboplastin?

Half lives: For Taxol, the half-life is dependent upon the length of the infusion. If it is a three hour infusion, the half-life is approximately 24 hours, but for a 24 hour infusion, it is about 52 hours. For carboplatin, the retention half life can be as much as 30 hours. Hope that helps. ...Read more

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What is the cost of herceptin (trastuzumab)?

What is the cost of herceptin (trastuzumab)?

Thousands!: In the us, the cost of Herceptin (trastuzumab) depends on who gives it to you and what kind of insurance you have. Patient's bills are in the range of $2000 to over &7000 per treatment. Why the difference? Medicare limits how much the cost can be "marked up" from the purchase price, but other insurance companies aren't as strict. So... The cost is what the market will bear, sadly. ...Read more

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What is Taxol (paclitaxel) typically used for?

What is Taxol (paclitaxel) typically used for?

Chemotherapy: Taxol (paclitaxel) is a very effective chemotherapeutic drug for the treatment of some forms of breast and ovarian cancer. ...Read more

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What exactly is the drug Taxol (paclitaxel) used for?

What exactly is the drug Taxol (paclitaxel) used for?

Chemotherapy: Taxol (paclitaxel) is a widely used chemotherapy drug for breast, lung, head/neck, esophageal cancers. ...Read more

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What are some contraindications of taxol (paclitaxel)?

What are some contraindications of taxol (paclitaxel)?

Not too many: Taxol (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to Taxol (paclitaxel) or other drugs made in cremophor el (polyoxyethylated castor oil). Taxol (paclitaxel) also should not be used in patients with solid tumors who have white counts of less than 1500 cells/mm3 or in patients with aids-related kaposi’s sarcoma with baseline white counts of less than 1000 cells/mm3. ...Read more

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Its been 4 mos now after my 12 session of herceptin (trastuzumab) , and I decided to continue my herceptin (trastuzumab), inorder to copmlete the cycle . Iis still helpful or effective after the 4 mos break?

Yea: After the hera trial was published and the data on trastuzumab was made available, everyone did not get trastuzumab. Once the data was published, the consensus was if it was less than a year, and the patient was her2 positive, one could still receive it. So yes, continue it. Probably the most effective drug for her2 positive disease. Hope this helps. ...Read more

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What causes herceptin (trastuzumab) headache?

What causes herceptin (trastuzumab) headache?

Let me explain: The thoery is Herceptin (trastuzumab) infusion cause contious vasodilatation which is thought to provoke the headache. ...Read more

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Are there any pine derivatives in herceptin (trastuzumab)?

Not that I am aware.: Herceptin (trastuzumab) is a bio-engineered monoclonal antibody treatment for her2 positive breast cancer patients. There are no known pine derivatives in this medicine of which I am aware. Hope that this is helpful. ...Read more

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Can Taxol (paclitaxel) cause diarrhea?

Can Taxol (paclitaxel) cause diarrhea?

Yes, it can: Diarrhea is one of the common side effects of paclitaxel. While common, it’s recommended that you contact your healthcare team if you have more than 4 - 6 episodes in a 24 hour period (unless your healthcare team gave you different instructions). ...Read more

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How does Taxol (paclitaxel) treat cancer?

How does Taxol (paclitaxel) treat cancer?

Inhibits division: Taxol (paclitaxel) is a chemotherapy drug that inhibits microtubules. This ends up inhibiting cell replication thereby making it difficult for cancer cells to continue dividing. ...Read more

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How can Taxol (paclitaxel) against the cancer?

How can Taxol (paclitaxel) against the cancer?

Kills cancer cells: Plclitaxel (taxol (paclitaxel) ) originally isolated from yew plant , inhibits cell division ( mitosis) normal perfect spindle assembly before it divides , is changed by Taxol (paclitaxel) cell will not proliferate and dies . It will do the same to normal cell also, you need expert oncologist to give a calculated dose to kill cancer cells only. ...Read more

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Dr. Wendy Askew
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Herceptin (Definition)

Herceptin ...Read more