Doctor insights on:
12 Weeks Of Taxol Herceptin How Bad Is It
What are side effects of low dose taxol with herceptin every week for 12 weeks i have stage 4 kidney disease and am concerned?
Yes, but...: Has your stage-4 kidney disease occurred before or after Herceptin with low dose of taxol? Herceptin is known to have significant adverse effects on to the kidneys and Taxol is not. So, it is good idea to ask your treating doctor for the specific profile possibly fitting you since s/he knows more about you than anyone online and will monitor your kidney function while receiving Herceptin. Best.... ...Read more
Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?
Yes: You have obviously survived the bilateral pulmonary emboli. You didn't mention being on Coumadin (warfarin) or any blood thinner but you should be if you are not(speak to your doctor). Hopefully, most of the clot on your lungs has dissolved. If you can't be on blood thinners for some reason, you could have a filter placed in your vena cava. Having cancer is a risk factor for having blood clots and pes. ...Read more
Less neuropathy: Unlike taxol, (paclitaxel) gemcitabine does not cause neuropathy. It can cause low platelets. It can also cause fluid retention. Also it is usually given 2 weeks on and 1 week off. Unlike Taxol (paclitaxel) which typically is given weekly. That is about it in regards to the difference. Hope this helps. ...Read moreSee 1 more doctor answer
After neoadj Taxol, (paclitaxel)A/C,herceptin,tumor shrunk by 1/3 but pathology shows lympho vascular invasion.How is this treated? Does it mean it's in my blood?
Lymph sac: it means that on the pathology slide they saw it in the blood/ lymph vessels ...Read more
Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?
Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read moreSee 3 more doctor answers
Due to financial constraint I only finished 12 session of herceptin (trastuzumab) instead of 17 . Is this ok or risky?
Half lives: For Taxol, the half-life is dependent upon the length of the infusion. If it is a three hour infusion, the half-life is approximately 24 hours, but for a 24 hour infusion, it is about 52 hours. For carboplatin, the retention half life can be as much as 30 hours. Hope that helps. ...Read more
Thousands!: In the us, the cost of Herceptin (trastuzumab) depends on who gives it to you and what kind of insurance you have. Patient's bills are in the range of $2000 to over &7000 per treatment. Why the difference? Medicare limits how much the cost can be "marked up" from the purchase price, but other insurance companies aren't as strict. So... The cost is what the market will bear, sadly. ...Read moreSee 1 more doctor answer
Not too many: Taxol (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to Taxol (paclitaxel) or other drugs made in cremophor el (polyoxyethylated castor oil). Taxol (paclitaxel) also should not be used in patients with solid tumors who have white counts of less than 1500 cells/mm3 or in patients with aids-related kaposi’s sarcoma with baseline white counts of less than 1000 cells/mm3. ...Read moreSee 1 more doctor answer
Its been 4 mos now after my 12 session of herceptin (trastuzumab) , and I decided to continue my herceptin (trastuzumab), inorder to copmlete the cycle . Iis still helpful or effective after the 4 mos break?
Yea: After the hera trial was published and the data on trastuzumab was made available, everyone did not get trastuzumab. Once the data was published, the consensus was if it was less than a year, and the patient was her2 positive, one could still receive it. So yes, continue it. Probably the most effective drug for her2 positive disease. Hope this helps. ...Read more
Kills cancer cells: Plclitaxel (taxol (paclitaxel) ) originally isolated from yew plant , inhibits cell division ( mitosis) normal perfect spindle assembly before it divides , is changed by Taxol (paclitaxel) cell will not proliferate and dies . It will do the same to normal cell also, you need expert oncologist to give a calculated dose to kill cancer cells only. ...Read moreSee 1 more doctor answer
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