Suisun City, CA
A 28-year-old female asked:
my husband was born with klinefelter's syndrome, and with only one testes.he doesn't produce enough sperm, do you think use of clomiphene will help?
3 doctor answers • 10 doctors weighed in
Pediatrics 46 years experience
Consult Endo: Klinefelter's are well known for a decline in natural testosterone production in adulthood. Consultation with an endocrinologist may be useful for general health. If your concern is for reproduction, it would be wise to visit a geneticist to review your family tree & review the potential outcomes of an assisted pregnancy between the two of you.
Fertility Medicine 19 years experience
No: Many men with klinefelters syndrome do not make an y sperm at all. Most men who do make sperm make very few, and usually ivf with icsi is required to become pregnant. The problem is actually testicular failure and so it is uncommon for medicine to help in boosting sperm counts. And children born to men with klinefelters also have an increased risk of genetic abnormalities - counseling is important.
Pediatric Urology 31 years experience
Doubtful: Fertility with klinefelter's is exceedingly difficult even with modern technology. Adding a solitary testis to the dilemma, diminishes this chance. Save your money and seek other options.
Last updated Jan 28, 2016
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
$15 per month
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.