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Red Oak, TX
A 54-year-old female asked:

Will taking benadryl (diphenhydramine) on a regular long term basis cause dental problems?

4 doctor answers5 doctors weighed in
Dr. Eyal Simchi
Specializes in Pediatric Dentistry
Maybe: A common side effect of many medications is dry mouth. Long term Benadryl (diphenhydramine) use can cause dry mouth which can cause you to be at higher risk for cavities. Sipping water throughout the day can help prevent that, as well as keeping up with regular home care and dental visits.
Dr. Thomas Mchugh
Specializes in Dentistry
Benadryl (diphenhydramine) : Benadryl, (diphenhydramine) an antihistamine , often causes drowsiness and has been used as a sleeping aid. It's primary negative affect orally is that it decreases salivary flow which can lead to increased bacterial adhesion to tooth structure. If you brush and floss before bed and when you wake in the morning, you should not have problems. 6 month cleanings and exams should be done regardless.
Dr. Laura Larch
Internal Medicine 19 years experience
Possibly: Taking an antihistamine can cause a dry mouth which can lead to more dental problems. It dries out the mucosal barrier which helps protect gums and teeth. Always tell your dentist what medications you are taking, even if it is over the counter.
Dr. Joseph Wineman
Dentistry 40 years experience
Too much benadryl (diphenhydramine): Benadryl (diphenhydramine) --antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing. It is also used to prevent and treat nausea, vomiting and dizziness caused by motion sickness. Can also be used to help you relax and fall asleep. Does not cause dental issues.

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Last updated Jun 18, 2016

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