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A 27-year-old male asked:

I am suffering from urticaria hives. my doctor have tried anti histaminics but of no use. ige test values were on higher side. what should i do?

3 doctor answers4 doctors weighed in
Dr. Michael Fisher
Dermatology 32 years experience
Chronic Hives: Omalizumab (xolair). This medication is normally given by injection to treat allergic asthma. It may help people who have chronic hives caused by an autoimmune response that haven't been helped by antihistamines. Only very small studies have been completed, so more clinical trials are needed.
Dr. John Chiu
Allergy and Immunology 57 years experience
Alternatives: First, has your doctor tried you on antihistamine up to 4 times daily? Other alternatives include immunomodulators, xoliar (a hybrid antibody to bind the ige), and some times a histamine-2 "blocker" or leukotriene modifier. An allergist would be your best option.
Dr. Michael Zacharisen
Allergy and Immunology 33 years experience
Identify trigger: Hives can be classified as acute or chronic. If ige tests are elevated, these should be determined if they are clinically relevant and avoidance measures started. Otherwise, treatment for hives includes higher than usual doses of antihistamines (h1), addition of h2 antihistamines, leukotriene modifier med. While Omalizumab may work it is very $$$$$$ and not covered by insurance for hives.

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Last updated Jun 30, 2014

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