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Clarksville, TN
A 35-year-old male asked:

Is there any link between adenosine deaminase deficiency and paraganglioma/ pheochromocytoma?

1 doctor answer2 doctors weighed in
Dr. Michael Engel
Pediatric Hematology and Oncology 20 years experience
Not that I'm ....: Aware of. Ada deficiency is one of the causes of severe combined immunodeficiency (aka, scid). Paraganglioma has been specifically correlated with mutations in succinate dehydrogenase (sdh) mutations, and likely reflects a link between cell growth/fate specification, epigenetic control of gene expression and metabolism.

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Last updated Aug 24, 2013

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