A 46-year-old female asked:
i have sle & ra, which runs in my family. 17 ye old daughter complains of aches & pains, being overly tired, esp when out in sun, should ii be worried?
2 doctor answers
Dr. David Greenfield answered
40 years experience Rheumatology
Concern is warranted: These diseases are often hereditary so it is reasonable to be somewhat concerned. I would advise evaluation by her physician.
Answered on Jun 28, 2013
Dr. Kurt Oelke answered
23 years experience Rheumatology
Depends: The twin concordance data suggests that the genetic penetrance conveys about a 10-20% risk in lupus. Therefore there is less than a 10% chance that your daughter will have lupus someday. The screening test for lupus (ANA) will probably not differentiate her clinical status therefore i would not pursue testing at this time. If however she started to develop more signs then i would order an ana.
Answered on Jun 10, 2014
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