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A 59-year-old male asked:

my prescription was just changed. would like to compare strength. 20 mgs of lisinopril equals about how many mgs of toprol (metoprolol)?

3 doctor answers3 doctors weighed in
Dr. Ankush Bansal
Internal Medicine 17 years experience
See below: They're not equivalent and there is no comparison between the two meds. Lisinopril is an ace inhibitor and toprol (metoprolol) is a beta blocker. They both can be used for hypertension but work in very different ways to accomplish that. If starting toprol (metoprolol), it needs to be titrated up until the desired effect is reached while monitoring for side effects.
Dr. Jack Rubin
Nephrology and Dialysis 48 years experience
Lisinopril and topro: You cannot compare the efficacy of different medications solely on their dosage compared in mgs. The drugs you mentioned are of different classes. The way they control hbp is also different, so they cannot be compared to each other by their dose in mgs. Their efficacy should based on how well each one controls your bp. Ask your doctor for more information.
Dr. Calvin Weisberger
Cardiology 51 years experience
Hypertension: Toprol (metoprol (metoprolol)ol) and Lisinopril have completely different mechanisms of action. It is thus not easy to predict comparable effect. The 20mg dose of Lisinopril is usually effective for Lisinopril so should yield BP effect, whether more or less than the toprol (metoprolol) dose in you awaits the trial in you.

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Last updated Jun 27, 2014
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