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A 37-year-old member asked:

What exactly is the role of protein phosphatase-1 in insulin to insulin receptor interaction?

1 doctor answer1 doctor weighed in
Dr. David Sneid
Endocrinology 42 years experience
Complex interaction: Phosphoprotein phosphatase is activated by the insulin, which indicates that there is a high concentration of glucose in the blood. The enzyme then acts to dephosphorylate other enzymes. The net effect is for glucose to enter the cell where it can be metabolized andlalso lowers the serum glucose level.

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Last updated May 13, 2013

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