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Reno, NV
A 50-year-old female asked:

My total protein had been climbing so dr ordered a protein electrophoresis. i have a slightly elevated serum kappa of 21.5. all else on test is normal, including normal kappa in urine and normal k/l ratio. possible reason for higher than normal kapp

1 doctor answer1 doctor weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Do not worry: Serum free light chain assay has a very limited usefulness other than invoking additional unwarranted testing. You asked this question earlier also. Forget your kappa level. Read this paper for info: Serum Free Light Chain Assay and κ/λ Ratio: Performance in patients without monoclonal gammopathies – High false positive rate. SINGH G. Amer J Clin Pathol. 2016; 146: 207-214

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Last updated Aug 28, 2020

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