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A 32-year-old female asked:

Ana factor increased from 1:320 to 1:640 over 2 years.rheumatologist says lupus tests clear.thinning of sclera.case of lupus and ms in family.worried.

2 doctor answers3 doctors weighed in
Dr. Gurmukh Singh
Pathology 50 years experience
Need to examine: Diagnosis of lupus depends on multiple criteria and it is best done by examining a person. You may visit this site for information: https://emedicine.medscape.com/article/332244-overview It would better to discuss the matter with your doctor who knows your health status better. Wish you good health!
Dr. David Greenfield
Rheumatology 41 years experience
ANA test result of 1:640 is not likely a false positive. In other words, it is significant enough to warrant additional evaluation. I would assume that your comment, "Rheumatologist says lupus tests clear" suggests he/she performed a battery of more specific tests and they were "negative". Neither Lupus not MS can be diagnosed exclusively by lab tests. Symptoms, signs, and exam are critical.

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Last updated Apr 11, 2021

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