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Dayton, OH
A female asked:

I am curious as to the reticulocyte values obtained in patients with sickle cell anemia. i am a laboratory worker so i see these quite often. unfortun?

3 doctor answers3 doctors weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Incomplete question: Reticulocyte count is higher in patients with hemolytic anemia as the body tries to make up for the shorter lifer span of red cells.
Dr. Clarene Cress
Specializes in Pediatrics
High retic=new cells: If there is a sudden drop in Hemoglobin, the bone marrow puts out new rbc's to compensate, and these take on stains differently and are know as reticulocytes. In sickle cell disease, there can be acute drop in Hgb related to sequestration of cells in the liver or spleen, etc. and there should be a high R, but if the bone marrow is suppressed due to drugs or infection, R wil be low.
Dr. Ed Friedlander
Pathology 44 years experience
What about them?: They are always high as sickle cells do not last so long as normals. If low. Aplastic crisis. If vey high, hemolysis is increased.

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Last updated Aug 22, 2017
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