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Frackville, Pennsylvania
A 56-year-old male asked:

I'm on my 3rd day of 25mg zoloft (sertraline) for ptsd and ocd. morning dosing and feel so tired by afternoon. can zoloft (sertraline) cause this fatigue?

1 doctor answer2 doctors weighed in
Dr. Jessica Langenhan
Psychiatry 16 years experience
Zoloft (sertraline) side effect: Zoloft (sertraline) doesn't always cause fatigue, but it is possible. Some people take Zoloft (sertraline) at bedtime, but it would be best to discuss this change in timing with your prescriber. Also, often the side effects that people have from Zoloft (sertraline) and other antidepressants resolve after the first 5-7 days on the medication, as your body adjusts to the medication, so keep this in mind as well.

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Last updated Sep 12, 2016

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