A 80-year-old male asked:
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can hypothermia in an elderly pt be a symptom of an acute transformation of overlap myeloproliferative/myelodysplacticty disorder? pt has hi wbc & crp

1 doctor answer
Dr. Rebecca Gliksman
37 years experience Internal Medicine
Hypothermia/mds: Elderly often feel cooler than younger individuals. Hypothermia ( how low?) may be a sign of infection /sepsis just like high fever. If one has myelodysplastic syndrome , would check for UTI, a common cause of infection,subtle pneumonia.Also check thyroid, adrenal function. Elevated WBC is a concern for sepsis and transformation. Go to the ER for blood cultures and evaluation.
Answered on Nov 28, 2017
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Dr. John Goldman
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Could be or infectio: He needs to be evaluated for an infection. He may be at more risk since he has the overlap syndrome.
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Reviewing a case: These little text boxes are not enough to review a complex case. You might consider having a consult with a physician here on HealthTap.
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A 80-year-old male asked:
Dr. Le Wang
Dr. Le Wang answered
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Try hypomethylating: CMML is common form of overlap syndrome, can be treated with hypomethylating agent (VADAZA) as MDS. Efficay? If acute transformation to acute leukemia ... Read More
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