A 54-year-old female asked:
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i am type 2 diabetic from last 7 yrs how safe is janumet (sitagliptin and metformin) 50/1000mg .i take it twice daily....

1 doctor answer
Dr. Julian Raffoul
Specializes in General Practice
Safe, however...: ... you should only take with regular monitoring by your doctor. Janumet (sitagliptin and metformin) is a combo-drug formed by adding sitagliptin (aka, Januvia) and metformin, hence the combo brand name (and combo price tag). It has a BLACK BOX WARNING for potential lactic acidosis which can occur due to metformin accumulation. This is rare, but fatal in 50% of cases, esp. in diabetics w/ kidney disease. Talk w/ your doctor.
Answered on Sep 13, 2015

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