A 33-year-old female asked:
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can i safely take rosuvastatin 40mg with ecosprin 75 mg for hyperlipidemia? other medication i'm on amlodipin 5, glimisave m2, vitd 60k, gemcal

1 doctor answer
Dr. Ward Dean
Dr. Ward Dean answered
42 years experience Anti-Aging Medicine
Yes, you can, but...: That's a bad combination. You've got two sulfonylurea drugs (which will cause weight gain, and wear out the pancreas) and a very low dose of Metformin. I recommend increasing your dosage of Metformin to 2,000 mg per day--and adding Acarbose (or white kidney bean extract). If your glucose is not under control, add only as much sulfonylurea as you need.
Answered on Jan 9, 2016
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3 comments
Dr. Ward Dean
Dr. Ward Dean commented
42 years experience Anti-Aging Medicine
Provided original answer
I don't recommend any of the statins. I use Niacin (Vitamin B3, nicotinic acid) 1500 mg/day. It's the safest, cheapest, most effective lipid lowering agent there is. It lowers cholesterol, triglycerides, and LDL--and raises HDL. It causes an unmistakable flushing initially, but this goes away with continued use--and can be minimized by taking an aspirin about 30 minutes before the niacin.
Feb 15, 2015
Dr. Rishi Vohora
18 years experience Cardiology
You don't recommend ANY Statin? Instead you recommend Meds that either show no outcome benefit or haven't been studied for outcomes?? I prefer double blind randomized trials that show benefits for PTs (especially high risk ones like this diabetic) but I guess that's just me...
Feb 15, 2015
Dr. Ward Dean
Dr. Ward Dean commented
42 years experience Anti-Aging Medicine
Provided original answer
You mean like: Canner, PJ, et al. Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin. J Am Coll Cardiol, 1986:8:1245-1255? In this long term study, niacin use resulted in 26% decrease in second non-fatal heart attacks over a six year period, and an 11% decrease in total mortality after 15 years of followup.
Feb 19, 2015

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