A 27-year-old male asked:
Can hydroxyurea cause polycythemia vera to mutate into leukemia?
1 doctor answer • 2 doctors weighed in
Hematology and Oncology 49 years experience
Controversial: There is a risk of transformation to acute leukemia just from having P Vera. But it is very low. Whether hydroxyurea increases that risk has not be definitively answered. Most hematologists find the benefit of controlling the disease greatly outweighs the risk. There is a new drug - Jakafi (ruxolitinib) - just approved for PV if not well controlled or if side effects of HU too great. Talk to your hematologist.
3.3k viewsReviewed >2 years ago
Last updated Mar 26, 2020
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.