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A 67-year-old female asked:

Can any targeted therapies or other drugs help with metastic colon cancer when xeloda (capecitabine) n irinotecan has failed ?

1 doctor answer1 doctor weighed in
Dr. Le Wang
Dr. Le Wanganswered
Internal Medicine 36 years experience
Yes: Target agents that have activity either as single agent or as combination for recurrent or refractory metastatic colon cancer as a second line include: Avastin (bevacizumab) or Cetuximab/Panitumumab (if k-ras, n-ras, b-raf are wide type) or Regorafenib (inhibitor of angiogenic receptor) or aflibercept. FOLFOX may be effective too after irinotecan has failed. Clinical trials are aslo available.

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Last updated Jan 23, 2015

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