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A 32-year-old male asked:

what tests can be done to diagnose diabetes insipidus? just vasopressin?

2 doctor answers5 doctors weighed in
Dr. Jeremy Gitomer
Nephrology and Dialysis 29 years experience
Water deprivation : The classic diagnostic test first is a first morning urine sample for osm after not drinking and if greater than 300 excludes the diagnosis. Water deprivation in the hospital stop intake and check serum/urine osm every 2 h. If serum sodium rises greater than145 wihtout rise in urine osm the diagnosis is made. Vasopressin is given if the urine osm increases it is central di if not nephrogenic di.
Dr. Samer Nakhle
Endocrinology 30 years experience
Dehydration test: The dehydration test is used to diagnose diabetes insipidus. This test is typically performed at an endocrinology office. It involves not drinking any liquids for 12 hours and then labwork is done in the morning and six hours later.
Dr. Jay Park
Dr. Jay Park commented
Pediatrics 50 years experience
"Water deprivation" test followed by vasopressin challenge to distinguish central vs nephrogenic DI.
Oct 4, 2013

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Excellent advice
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