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A 28-year-old male asked:

what is the definition or description of: fibrinogen levels low?

2 doctor answers4 doctors weighed in
Dr. Viraj Lakdawala
Emergency Medicine 14 years experience
Multiple reasons.: There are multiple possible causes of low fibrinogen levels including: end-stage liver disease, severe malnutrition, congenital afibrinogenemia or hypofibrinogenemia, severe infections resulting in consumption of fibrinogen, medications that may impair hepatic synthetic function including valproic acid or l--asparaginase.
Dr. Michael Dugan
Specializes in Hematology
A low fibrinogen: Level is a risk factor for serious bleeding. This can occur on a congenital basis, but the much more common circumstance is acquired, for example following chemotherapy for acute leukemia. The level is augmented with cryoprecipitate -- a plasma derived product which is rich in fibrinogen.

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A 48-year-old member asked:

What is low d-dimer by high fibrinogen?

1 doctor answer2 doctors weighed in
Dr. Lewis Hassell
Pathology 39 years experience
Clotting proteins: D-dimer is a breakdown product of fibrin that has been crosslinked, thus in elevated levels it indicates active clot lysis. Fibrinogen is a clotting factor normally present in the blood and needed to make fibrin, an essential part of a clot. In some settings, fibrinogen will go up in response to inflammatory or other stimuli.
A 39-year-old member asked:

Please answer! what does a low d-dimer by high fibrinogen mean?

1 doctor answer1 doctor weighed in
Dr. Lawrence Presant
Phlebology 41 years experience
Clots coming ; going: D-dimer is increased with breakdown of clots to crosslinked fibrin. Fibrinogen forms fibrin whose fibers become crosslinked to form a clot. So high fibrinogen infers clot formation, not breakdown, so d-dimer is inferred to be low.
A 38-year-old member asked:

Why does fibrinogen tend to be higher in tumor patients?

1 doctor answer2 doctors weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Tissue injury: Any tissue injury is associated with elevation in fibrinogen. Most clinically evident tumors have areas of necrosis and that can be a trigger for elevation of fibrinogen. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex.
United Kingdom
A 25-year-old female asked:

Really scared gp not concerned my fibrinogen derived was 5.4 with cormal rage below 4.7 my aptr was 45.2 normal under 36.5 should i be scared plzzz?

1 doctor answer2 doctors weighed in
Dr. Ed Friedlander
Pathology 44 years experience
Big picture : Fibrinogen levels flucuate, are often high if you have significant inflammation, and a young woman's levels may rise at the same time each month. I suggest you recheck when in your usual state of health. If the activated partialntheomboplastin time is still up, get checked for anti phospholipid antibody and/or specific factor deficiencies as appropriate.
United Kingdom
A 26-year-old female asked:

My fibrinogen level is 5.4 cut of 4.7 is this dangerous my appt is also increased 45.2 cut of 36.5 really scared ?

1 doctor answer1 doctor weighed in
Dr. Luis Villaplana
Internal Medicine 35 years experience
Circulating Anticoag: If you meant aPTT, you may have what's called a circulating amici agility. Do not be scared. Ask questions, see a hematologist for further testing. Most times, aspirin daily is all you need. Please seek all the information you can get. Until you have answers, DO NOT GET PREGNANT, and maybe take a baby aspirin daily until further advised by your doctors

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Last updated Nov 28, 2017
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