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A 44-year-old member asked:

what is the cause of edward's syndrome?

2 doctor answers4 doctors weighed in
Dr. David Rosenfeld
Pain Management 27 years experience
Trisomy 18 : Edwards syndrome (also known as trisomy 18 (t18)) is a genetic disorder caused by the presence of all or part of an extra 18th chromosome. This genetic condition almost always results from nondisjunction during meiosis. It is named after john h. Edwards, who first described the syndrome in 1960. It is the second most common autosomal trisomy, after down's syndrome, that carries to term.
Dr. James Ferguson
Pediatrics 46 years experience
Defective transfer: When eggs/sperm form they go through a process where the pairs of chromosomes split.Each resulting egg or sperm should only have one of the pair. When /if an egg or sperm fails to drop one or part of the chromosome 18, it will have excessive material once conception occurs.That extra material interferes with normal development.

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A 45-year-old member asked:

What is the mode of inheiritance for edward's syndrome?

2 doctor answers7 doctors weighed in
Dr. Golder Wilson
Specializes in Clinical Genetics
Chromosomal: Edwards syndrome is usually due to trisomy 18 (extra copy of chromosome #18) that is an accidental occurrence with low recurrence risk (<1%) to the parents. Occasionally a translocation is found and the parents need testing to see if they have a balanced translocation (no symptoms) with higher recurrence risk.
A 45-year-old member asked:

My friends baby died from edwards syndrome. What is that?

3 doctor answers4 doctors weighed in
Dr. James Ferguson
Pediatrics 46 years experience
Extra chromosome 18: The edward syndrome, named after a researcher who reported the features in 1960, applies to babies born with all or most of an extra 18 chromosome. Half die in the first week & only 5-10% make it past 1 year of age. The extra chromosomal material is in every cell of the body and distorts the formation of major organ systems to the point that longer survival is impossible regardless of treatment.
A 43-year-old member asked:

How does edwards syndrome affect a baby?

2 doctor answers5 doctors weighed in
Dr. Nela Cordero
Pediatrics 54 years experience
TRISOMY 18: Edwards syndrome or trisomy e is caused by extra chromosome 18 consisting of mental retardation, severe microcephaly and many developmental anomalies.
A 43-year-old member asked:

What's the incidence of edward syndrome?

2 doctor answers3 doctors weighed in
Dr. David Rosenfeld
Pain Management 27 years experience
One in 6,000: Edwards syndrome occurs in around one in 6, 000 live births and around 80 percent of those affected are female. The majority of fetuses with the syndrome die before birth. The incidence increases as the mother's age increases. The syndrome has a very low rate of survival, resulting from heart abnormalities, kidney malformations, and other internal organ disorders.
A 46-year-old member asked:

Is there a cure for edwards syndrome trisomy?

2 doctor answers3 doctors weighed in
Dr. James Ferguson
Pediatrics 46 years experience
No: Those with a standard trisomy have the abnormality in every cell of their body. The vast majority will die within the first year from one of many major congenital abnormalities with this defect.

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Last updated Apr 24, 2016

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