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A 46-year-old member asked:

Is one injection of epinephrine enough to treat an allergic reaction?

2 doctor answers5 doctors weighed in
Dr. Manav Singla
Allergy and Immunology 23 years experience
Some need seconds: Some people may need a second injection of epinephrine, so always keep second Epipen handy or make sure you know how to use the second dose in your twinject.
Dr. Monica Vasudev
Allergy and Immunology 26 years experience
The Epipen comes as a twin pack which is easy to administer.
Dec 6, 2012
Dr. Michael Zacharisen
Allergy and Immunology 33 years experience
Usually: About 25% of anaphylactic reactions will require a second dose of epi due to a dual or late phase reaction. If the epi is given in a timely manner, the immediate reaction should improve. However, a second dose can be given 5-10 minutes later if necessary. In my allergy experience (19 years) i've rarely needed to give a second dose---anecdotal.

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Last updated Jun 6, 2015

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