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A 28-year-old member asked:

How much lifespan does a child have who is suffering from major thalassemia?

2 doctor answers4 doctors weighed in
Dr. Robert Kwok
Pediatrics 33 years experience
Beta: 20's to 30's: Alpha thalassemia major is fatal before birth in almost all cases. Beta thalassemia major babies look normal at birth. Symptoms start after age 6-8 months. If good treatment starts then, with regular transfusions, plus chelation to remove excess iron, patients can survive into their 20's and 30's. Medical care and technologies improve over time, so that patients today may live longer than before.
Dr. Della Howell
Pediatric Hematology and Oncology 23 years experience
It varies: Beta-thal major is a serious blood disorder that requires significant medical care. These children require regular blood transfusions and then treatments to keep their body from holding on to too much iron from these transfusions. Some children are cured of this disease with a bone marrow transplant, and if successful, may have a normal life span, but not all children are eligible for transplant.

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Similar questions

CA
A 24-year-old member asked:

What is the lifespan for a child have suffering from major thalassemia?

2 doctor answers5 doctors weighed in
Dr. Robert Kwok
Pediatrics 33 years experience
Beta: 20's to 30's: Alpha thalassemia major is fatal before birth in almost all cases. Beta thalassemia major babies look normal at birth. Symptoms start after age 6-8 months. If good treatment starts then, with regular transfusions, plus chelation to remove excess iron, patients can survive into their 20's and 30's. Medical care and technologies improve over time, so that patients today may live longer than before.
Dr. Scott Miller
Pediatric Hematology and Oncology 45 years experience
Or maybe longer if compliance with chelation is good. Stem cell transpllant may be possible, and it seems gene therapy might finally be at hand.
Jan 31, 2012
Dr. Jay Park
Dr. Jay Park commented
Pediatrics 50 years experience
Life span has extended to 50's and 60's with advancement of chelation therapy. Bone marrow transplantation has also cured thousands of children who have thalassemia major.
Nov 10, 2018

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Last updated Jun 24, 2014
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