A 49-year-old member asked:
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what genes cause hereditary ovarian cancer?

1 doctor answer
Dr. Golder Wilson
Specializes in Clinical Genetics
BRCA 1 and 2: The breast-ovarian cancer (brca 1 and 2) genes are the only ones so far proven to cause susceptibility to ovarian cancer (as high as 50% lifetime risk for ovarian, 85% for breast cancer if you have a mutation. Other ovarian cancer susceptibility genes may be identified by ongoing research.
Answered on Apr 16, 2016
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1 comment
Dr. Carlos Encarnacion
34 years experience Medical Oncology
Patients with Hereditary Non Polyposis Colorectal Cancer Syndrome also have increased risk for ovarian (in addition to endometrial) cancer albeit not as much as BRCA carriers.
Sep 2, 2013

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