U.S. doctors online nowAsk doctors free
A 30-year-old member asked:

if i have hla-b27 gene and sacroilitis will i develop ankylosing spondylitis?

2 doctor answers6 doctors weighed in
Dr. Thomas Dowling
Orthopedic Spine Surgery 40 years experience
Not necessarily: There are people who carry the hla b27 but have no symptoms & just having si. Joint pain does not mean you will have as but you should get evaluared by a rheumatologist as you have 2 key findings.
Dr. Thomas Namey
Rheumatology 48 years experience
If you are B27+: If b27 positive with clinical and radiographic sacroiilitis, you have as. But most patients do not ankylose. Therefore the "name" is somewhat archaic. But treating for pain is inappropriate. Other drugs are needed to suppress inflammation, both for preventing other rheumatic problems, and heart disease and stroke!
Dr. Peter Ihle
Dr. Peter Ihle commented
Orthopedic Surgery 54 years experience
A short course of Indocin can B diagnostic & treatment for ankylosing spondylitis.
Jun 22, 2013

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
$30 per visit with
membership

Similar questions

CA
A 21-year-old member asked:

Is sarcoidosis a genetic disease? Will my children get it?

3 doctor answers5 doctors weighed in
Dr. Marci Dietrich
Bariatrics 41 years experience
Family sarcoid: There is about a16% incidence of family members having sarcoidosis, twins are a higher incidence.I believe that the susceptibility is genetically linked to the immune system.There does not seem to an increased incidence between mates. Sarcoid is not considered contagious.Childhood sarcoid is considered rare, but difficult to diagnose.Some milder symptoms are dry eyes, dry skin, salivary glands prob.
A 21-year-old member asked:

Does genetic play a role hearing loss susceptibility to aminoglycosides in children or adults?

2 doctor answers8 doctors weighed in
Dr. Michael Olds
ENT and Head and Neck Surgery 32 years experience
Genetic hearing loss: Yes, a genetic mutation in mitochondrial RNA has been shown to predispose individuals to hearing and balance problems when they receive amino glycoside antibiotics. This can happen even at low doses typically acknowledged to minimize the risk of toxicity. At high doses, however, amino glycosides can exhibit toxicity in the ear even in individuals without this mutation.
A 21-year-old member asked:

Is high blood pressure genetically heritable?

1 doctor answer1 doctor weighed in
Dr. John Szawaluk
Cardiology 31 years experience
Frequently: Yes. If there is a history of hypertension in first degree relatives your risk for hypertension certainly increases.
A 21-year-old member asked:

What genes play an important role in coronary vascular (artery) disease?

2 doctor answers4 doctors weighed in
Dr. Robert Kwok
Pediatrics 33 years experience
Genes play a role: Researchers are currently trying to identify genes that increase one's risk for getting artery disease and heart attacks. By looking at families who have several generations with such diseases, researchers have found certain genes are involved. Some genes cause cholesterol levels to stay high. The challenge now is to figure out how each of the identified genes leads to artery disease and blockage.
A 21-year-old member asked:

How do genes influence colon cancer risk?

2 doctor answers8 doctors weighed in
Dr. Eric Kaplan
Colon and Rectal Surgery 42 years experience
Depends: Family history and thus genes can account for approximately 20% of all colon cancers.

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
$30 per visit with
membership
Last updated Jun 22, 2013

People also asked

Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
$30 per visit with
membership

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.