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A 30-year-old female asked:

If my husband has hemoglobin f and i have philadelphia hemoglobin, can we still have a baby?

2 doctor answers2 doctors weighed in
Dr. James Ferguson
Pediatrics 46 years experience
Your ?? raises ??: We all have some hemoglobin f, that's what a fetus makes & the percentage drops after birth in most. Some varients of sickle cell can have higher persisting levels of HGB f , so i wonder if there is another issue here.The HGB g philadelphia is usually not a big problem.I would contact a genetic counselor through a medical school or children's hospital & find out for sure.
Dr. Gurmukh Singh
Pathology 49 years experience
Agree with DR. F: From what you described there is nothing precluding you from having a baby, but it is imperative that you consult a genetic counselor assess the risk to the baby.

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Last updated Mar 24, 2019

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