A 63-year-old member asked:
need some basic knlowledge about consolidations chemo treatments for aml npm1 after the first two chemo treaents in the hospital .?
2 doctor answers
Dr. William A Biermann answered
46 years experience Medical Oncology
Usually cytarabine: This mutation is associated with responsiveness to chemotherapy. The typical treatment for consolidation is Cytarabine in high dose. There other other types of consolidation programs. Your oncologist should discuss the options in detail.
Good luck.
Answered on Jun 24, 2014
Dr. Christopher Cogle answered
24 years experience Hematology and Oncology
AML Consolidation: If an AML has uninformative chromosome testing results (also reported as "normal") and the only gene mutation is NPM1, then treatment typically involves one cycle of induction (such as 7+3) followed by 4 cycles of consolidation chemotherapy with High Dose Ara-C (aka HiDAC). Many times this plan requires modifications because of side effects, infections, etc.
Answered on Sep 17, 2014
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