A 39-year-old member asked:
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what needs to be present for the diagnosis of pml?

2 doctor answers
Dr. Ian Stein
Dr. Ian Stein answered
21 years experience Neurology
MRI: There are characteristic MRI findings. Certain test can be done on spinal fluid too.
Answered on Jun 10, 2014
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Dr. Bennett Machanic
52 years experience Neurology
Immune suppression: The jc virus is present in at least 60% of normal individuals and truly does little thruout our lifetimes. Pts with HIV infections, or individuals being treated with cancer chemotherapies, or other immune-suppressants are also at risk. Tysabri (natalizumab) for ms is also a provocateur. Testing of blood or spinal fluid can be confirmatory, and a brain MRI can be characteristic.
Answered on Jun 10, 2014

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