A 39-year-old member asked:
what needs to be present for the diagnosis of pml?
2 doctor answers
Dr. Ian Stein answered
21 years experience Neurology
MRI: There are characteristic MRI findings. Certain test can be done on spinal fluid too.
Answered on Jun 10, 2014
1
1 thank
Dr. Bennett Machanic answered
52 years experience Neurology
Immune suppression: The jc virus is present in at least 60% of normal individuals and truly does little thruout our lifetimes. Pts with HIV infections, or individuals being treated with cancer chemotherapies, or other immune-suppressants are also at risk. Tysabri (natalizumab) for ms is also a provocateur. Testing of blood or spinal fluid can be confirmatory, and a brain MRI can be characteristic.
Answered on Jun 10, 2014
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A 34-year-old member asked:
Dr. Anthony Mosley answered
24 years experience Neurology
MRI & biopsy: The pattern on MRI of the brain can be very suggestive, but a biopsy (surgery to get brain tissue to examine) is the only way to definitively diagnose ... Read More
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A 38-year-old member asked:
A Verified Doctor answered
A US doctor answered Learn more
MRI and spinal tap: Progressive multifocal leukoencephalopathy has a characteristic appearance on on a brain mri. A lumbar puncture (spinal tap) is used to look for the v ... Read More
3
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A 31-year-old member asked:
Dr. Larry Armstrong answered
27 years experience Neurosurgery
MRI, spinal fluid: Mri, clinical exam, pathologic tissue and spinal fluid are all tests for progressive multifocal leukoencephalopathy. It depends on the presentation a ... Read More
A 33-year-old member asked:
Dr. Jonathan Dissin answered
39 years experience Neurology
NO: Pml is caused by the jc virus. It can lie dormant in an immunocompetent host for a lifetime. In the immunocompromised host, pml is uniformly fatal wit ... Read More
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