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A 31-year-old member asked:

how could a cancerous condition in the body be related to the development of severe reduction in bone mass?

2 doctor answers3 doctors weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Steroids: Some tumors produce acth like chemical that increases production of corticostoids and the later cause bone loss. Other facots may be cancer related cachexia, inadequte intake of calcium and vitamin d.
Dr. Christian Schultheis
Hematology and Oncology 24 years experience
Cytokines: There are certain enzymes in the body which affect metabolism of other organs, one of these is the bones. For example, a certain cancer called multiple myeloma causes an increase in osteoclast activity which leads to bone destruction. Also some of the treatment can cause decreased bone formation.

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Last updated Jul 28, 2012
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