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A 32-year-old member asked:

Does pernicious anemia run in families?

2 doctor answers5 doctors weighed in
Dr. Ritesh Rathore
Hematology and Oncology 30 years experience
Rarely: Most cases of pernicious anemia are acquired due to immune destruction of the stomach cells which produce intrinsic factor. This results in poor absorption of B12 from food and patients get anemic as a result. Only rarely can children get this as a congenital causes.
Dr. Julio Hajdenberg
Hematology and Oncology 31 years experience
Sometimes: Pernicious anemia (pa) is a horrible misnomer for what should be called autoimmunity mediated deficiency of b12. It is well known that autoimmune conditions (rheumatoid arthritis, hypothyroidism, vitiligo , pa and others)run in families. Therefore it is not common to have family members that develop different autoimmune conditions as they age, including pa.

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Last updated Jul 25, 2014

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