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A 35-year-old member asked:

Is it possible for someone to have high hemoglobin and also a vitamin b12 deficiency?

2 doctor answers5 doctors weighed in
Dr. Scott Bolhack
Wound care 35 years experience
B12 Deficiency: There are several things that happen with a B12 deficiency including anemia, neuropathies, and non-soecific neurological affects such as fatigue, depression, irritability, and psychosis. You ask an excellent question. Through research, i could not find any whether the neurological symptoms could occur before the anemia. Clinically, patients are diagnosed with B12 deficiency through anemia first.
Dr. Jason Burke
Anesthesiology 25 years experience
It is possible: B12 deficiency generally leads to low hemoglobin levels. But, if a person lives at a high altitude (over 6500 feet, ) they could have a high hemoglobin level if the B12 deficiency is mild. There are also other diseases that cause a high hemoglobin level, such as polycythemia vera.
Dr. Liawaty Ho
Dr. Liawaty Ho commented
Hematology and Oncology 23 years experience
high hemoglobin can also be caused by other condition such as sleep apnea, liver /kidney cyst and causing secondary polycythemia and vit B12 deficiency can still develop as a separate entity to the elevation of hemoglobin. and as Dr. Burke pointed- in polycythemia vera- hb can be elevated and vit B12 can still be deficient due to other mechanism and as a separate condition.
Jan 8, 2013

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