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A 52-year-old member asked:

Does alpha thalassemia trait have gene therapy available?

2 doctor answers3 doctors weighed in
Dr. Robert Kwok
Pediatrics 33 years experience
No: Alpha thalassemia trait only causes mild anemia, and the person usually has no symptoms. Gene therapy is not available and would not be needed.
Dr. Bachar Al-Alami
ADHD and Autism 36 years experience
Not Yet ?Read: Since all normal hemoglobins of postnatal life contain Alpha chains, homozygous Alpha (0) thalassemia (ie, loss of all four Alpha globin genes) is incompatible with extrauterine life, leading to hydrops fetalis and/or death shortly after delivery, unless blood transfusion and/or hematopoietic cell transplantation can be performed in time.

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Last updated Apr 16, 2017
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