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A 39-year-old member asked:

What is the test for: alpha-fetoprotein, estriol. human chronic gonadotropin, inhibin a ?

2 doctor answers4 doctors weighed in
Dr. Rakhi Dimino
Specializes in Obstetrics and Gynecology
Quad screen: This is a blood test usually done between 15 and 20 weeks of pregnancy. It tries to calculate the risk of the baby having down's syndrome, another genetic disorder called trisomy, or open spina bifida. It cannot tell you for sure if the baby has these, just if you are at increased risk. There are definitely some false negatives (rare) and false positives (common).
Dr. Nikolaos Zacharias
Maternal-Fetal Medicine 26 years experience
QUAD screen.: Historically performed between 16-20 weeks, the maternal serum quadruple screen (quad) is likely to fall by the wayside now that cell-free fetal dna can actually be tested from the maternal blood (maternit21 and others). Quad is a screening - not diagnostic - test.

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A 38-year-old member asked:

Whats the test for alpha-fetoprotein estriol human chronic gonadotropin inhibin a ?

1 doctor answer2 doctors weighed in
Dr. Michael Murray
Fertility Medicine 28 years experience
Quad Screen: This non-invasive prenatal screening blood (serum) test is done around 12 weeks gestation to see if the fetus may have down's syndrome (trisomy 21) or trisomy 18. It is often combined with a transvaginal ultrasound for better accuracy. This test is not diagnostic. If the screening test is worrisome, then an amniocentesis is usually recommended.

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Last updated Mar 26, 2013
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