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A 41-year-old member asked:

Thyroid scan/uptake shows mild hyperthyroidism, blood-work shows hypothyroidism. what's up with that?

2 doctor answers3 doctors weighed in
Dr. Pradeep Singh
Family Medicine 24 years experience
Thyroiid scan unhelp: Thryroid scans do not help with hormonal status of the gland.
Dr. Susan Wingo
Endocrinology 33 years experience
Labs are right: Thyroid scan/uptake shows how active someone's thyroid is in trapping iodine, but not whether or not their thyroid is able to convert iodide to iodine and make thyroid hormone with it. In this situation, the labs tell the true story - that the thyroid can't make enough thyroid hormone. Uptakes and scans are morehelpful in people with hyperthyroidism, and don't add much info in hypothyroidism.

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A 31-year-old member asked:

My thyroid scan/uptake shows mild hyperthyroidism, but blood-work shows hypothyroidism. Does this happen often? What should I do?

2 doctor answers3 doctors weighed in
Dr. Robert Carroll
Nuclear Medicine 53 years experience
Reverse T3 (liothyronine): Thyroid scan/uptake shows mild hyperthyroidism, but blood-work shows hypothyroidism. Thyroid gland is working hard but producing ineffective hormone. Test for reverse t3 (liothyronine). Thyroid hormone replacement is reasonable. Possible mutations in the sbp2 gene: abnormal thyroid function tests, low triiodothyronine (t3 (liothyronine)), high thyroxine (t4) and reverse t3 (liothyronine), and slightly elevated thyrotropin.

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Last updated Dec 19, 2015

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