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A 40-year-old member asked:

can immune globulin shot prevent hepatitis a after exposure?

1 doctor answer1 doctor weighed in
Dr. Dan Fisher
Internal Medicine 27 years experience
Yes: Both hep a vaccine and Immune Globulin are approved for post exposure prophylaxis. Choice depends upon host factors and availability.

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A 45-year-old member asked:

If immune globulin is given one week in advance of exposure will it prevent hepatitis a?

1 doctor answer1 doctor weighed in
Dr. Javier Chinen
Pediatric Allergy and Asthma 30 years experience
Depends on dose: Immunoglobulin preparations are not checked if they have protective level antibodies anti-hepatitis a. Assuming that most blood donors have enough antibodies anti-hepatitis a, the immunoglobulin preparations should also have enough to neutralize a potential infection. However, this is especulation and it is possible that there could be enough viruses to overcome the neutralzing antibodies received.

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Last updated Jun 25, 2014

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