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A 28-year-old male asked:

Doesprazosin/other alpha blocks act on non-vascular smooth muscle e.g. the throat?if sudafed is alpha stim and contricts nasal,wouldnt it make sense?

1 doctor answer1 doctor weighed in
Dr. Donald Colantino
Internal Medicine 61 years experience
Good question: Alphablockers used to treat hypertension seem to be specific for their action on arteriolar musculature as far as I can tell clinically. Sudafed constricts smooth muscle in vessel walls, but can stimulate smooth muscle in the lower urinary tract and cause urinary retention at times. A pharmacologist would be best qualified to answer your question however.

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Last updated Jan 6, 2015

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