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A 37-year-old member asked:

Is matulane (procarbazine) useful to non-hodgkin's lymphomas?

1 doctor answer7 doctors weighed in
Dr. Ed Kaplan
Hematology and Oncology 39 years experience
No: Only indication is for hodkin's disease, and even in that condition, where it is used as part of the "mopp" regimen, it has been replaced by other regimens. It may have slight activity in other lymphomas but there are now many other effective chemotherapeutic and biologic choices.
Dr. Andrew Turrisi
Radiation Oncology 47 years experience
It's other name is Procarbazine. It is the P in the PCV regimen used in pediatric brain tumors. It is an alkylating agent, causes cross links in dna damage.
Jun 7, 2012

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Last updated Jun 10, 2012

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