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A 51-year-old member asked:

which forms of leukemia are caused by a mutation?

1 doctor answer1 doctor weighed in
Dr. Sewa Legha
Medical Oncology 50 years experience
Most are due to muta: Mutations are common in all cancers. In Leukemia the very first mutation(Single mutation, causing cancer was discovered in Chronic Myelocytic Leukemia(CML). In most other Leukemias, there are multiple mutations present once we have learned how to search for them by Genomic profiling.

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A 21-year-old member asked:

What is acute lymphoblastic leukemia (all)?

4 doctor answers11 doctors weighed in
Dr. Stephen Noga
Medical Oncology 34 years experience
Lymph system cancer: Lymphocytes are normal cells of the immune system that protects the body from infection. When these cells become cancerous, they grow out of control in the bone marrow, blood and other organs. All is very common in children but can occur in adults. With children, it is truly one of our success stories thanks to clinical trials with cure rates above 90%. Adults do not do as well.
A 33-year-old member asked:

Can you have leukemia and not anemia?

2 doctor answers7 doctors weighed in
Dr. Michael Thompson
Hematology and Oncology 20 years experience
Yes: Advanced leukemia of any sort (aml, all, cml, cll) can lead to anemia. However, early leukemia (rai 0 cll) may not result in anemia.
A 53-year-old member asked:

I want to know what is the difference between anemia and leukemia?

2 doctor answers7 doctors weighed in
Dr. Michael Thompson
Hematology and Oncology 20 years experience
Different cells: Emia = blood. An-emia = lack of red blood cells (low hgb) associated with fatigue leukocytosis = more white blood cells (WBC) in the blood. One cause of leukocytosis is an increase in WBC cancer cell called leukemia.
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A 42-year-old member asked:

Is it possible for someone to have leukemia and not anemia?

2 doctor answers6 doctors weighed in
Dr. Stephen Noga
Medical Oncology 34 years experience
Yes: Depending on the type of leukemia, this is possible. For example, chronic lymphocytic leukemia is a slowly prgressive disease and it may take a while before the marrow becomes significantly involved to the point of affecting the red blood cells. Also, in the early stages of leukemia, anemia may not be present.
A 44-year-old member asked:

Could hemophilia occur due to a mutation?

2 doctor answers7 doctors weighed in
Dr. Robert Kwok
Pediatrics 33 years experience
Yes, a gene mutation: Hemophilia "A" is a hereditary bleeding disorder where there is a deficiency in clotting factor VIII (factor VIII is needed for blood clotting). It is inherited on the X-chromosome (sex-linked). Men only have 1 "X", so if their "X" is mutated, they will have the disease. Women have 2 "X's", so they can have 1 mutated "X" and 1 normal "X", and be a carrier of the disease, with mild or no symptoms.

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Last updated Oct 7, 2015

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