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A 38-year-old member asked:

What kind of disease is lupus? what causes it?

1 doctor answer2 doctors weighed in
Dr. Amit Golding
Rheumatology 19 years experience
SLE diagnosis: Systemic lupus erythematosus is best diagnosed by an experienced rheumatologist. It is an autoimmune disease. A high-titer ANA, >1:320 is both sensitive and specific for lupus. Other auto-antibodies can help to confirm the lupus diagnosis. Anti-Smith is highly specific for lupus but not very sensitive. Anti-dsDNA is also highly specific and tends to be seen in lupus with kidney involvement.

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Last updated Jun 20, 2015
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